Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2011-02-15
2011-02-15
Landsman, Robert (Department: 1647)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007210
Reexamination Certificate
active
07888045
ABSTRACT:
The invention provides isolated nucleic acid and amino acid sequences of taste cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of taste cell specific G-protein coupled receptors.
REFERENCES:
patent: WO 93/16178 (1993-08-01), None
patent: WO 98/13478 (1998-04-01), None
patent: WO 99/42470 (1999-08-01), None
patent: WO 00/38536 (2000-07-01), None
Höfer, D., et al., “Taste receptor-like cells in the rat gut identified by expression of α-gustducin,”Proc. Nat'l. Acad. Sci. USA, vol. 93, pp. 6631-6634 (Jun. 1996).
Ming, D., et al., “Characterization and solubilization of bitter-responsive receptors that couple to gustducin,”Proc. Nat'l. Acad. Sci. USA, vol. 95, pp. 8933-8938 (Jul. 1998).
Ming, D., et al., “Blocking taste receptor activation of gustducin inhibits gustatory responses to bitter compounds,”Proc. Nat'l. Acad. Sci. USA, vol. 96, pp. 9903-9908 (Aug. 2008).
Journal of Cookery Science of Japan, vol. 30(2), pp. 68-73 (1997) (no translation available).
Ogura, T., et al., “Bitter taste transduction of D natonium in the mudpuppyNecturus maculosus,” The Journal of Neuroscience, vol. 17(1), pp. 3580-3587 (May 15, 1997).
Sambrook, J., et al.,Molecular Cloning: a laboratory manual, 2nd Edition, Cold Spring Harbor Laboratory Press, pp. 17.3-17.44 (1989).
Adams, et al. “Use of a random human BAC End Sequence Database for Sequence-Ready Map Building; CITBI-E1-2530B8.TF CITBI-E1Homo sapiensgenomic clone 2530B8, genomic survey sequence”EMBLDatabase Entry AQ308694; Accession No. AQ308694 (Dec. 23, 1998).
Adams, Mark D. et al.; “Sequence Identification of 2,375 Human Brain Genes”;Nature, pp. 632-634, vol. 355 (Feb. 13, 1992).
Adler, et al. “A Novel Family of Mammalian Taste Receptors”Cellvol. 100, pp. 693-702, (2000).
Bork, P., et al., “Go hunting in sequence database but watch out for traps,”Trends in Genetic, vol. 12, pp. 425-427 (1996).
Bork, P., “Powers and pitfalls in sequence analysis: the 70% hurdle,”Genome Research, vol. 10, pp. 398-400 (2000).
Brenner, S., “Errors in genome annotation,”Trends in Genetics, vol. 15, pp. 132-133 (1999).
Brown et al.: “Cloning and characterization of an extracelluar Ca2+—sensing receptor from bovine parathyroid”Letters to Nature366: 575-580 (Dec. 9, 1993).
Cao et al: “Cloning and localization of two multigene receptor families in goldfish olfactory epithelium”Proc. Natl. Acad. Sci. 95 11987-11992 (Sep. 1998).
Chandrashekar, et al. “T2Rs Function as Bitter Taste Receptors”Cellvol. 100, pp. 703-711, (2000).
Chaudhari et al: “The Taste of Monosodium Glutamate: Membrane Receptors in Taste Buds”Journal of Neuroscience16(12): 3817-3826 (Jun. 15, 1996).
Doerks, T., et al., “Protein annotation: detective work for function prediction,”Trends in Genetics, vol. 14, pp. 248-250 (1998).
Dulac and Axel: “A Novel Family of Genes Encoding Putative Pheromone Receptors in Mammals”Cell83 195-206 (Oct. 20, 1995).
Herrada and Dulac: “A Novel Family of Putative Pheromone Receptors in Mammals with a Topographically Organized and Sexually Dimorphic Distribution,”Cell90: 763-773 (Aug. 22, 1997).
Hillier et al., “The DNA sequence of human chromosome 7”,Nature, pp. 157-164, vol. 424 (2003).
Hoon et al.: “Putative Mammalian Taste Receptors: A Class of Taste-Specific GPCRs with Distinct Topographic Selectivity”Cell96 541-551 (Feb. 19, 1999).
Hoon and Ryba: “Analysis and Comparison of Partial Sequences of Clones from a Taste -bud enriched cDNA Library ”J. Dent Res. 76: 831-838 (Apr. 1997).
Kim et al., “Positional Cloning of the Human Quantitative Trait Locus Underlying Taste Sensitivity to Phenylthiocarbamide”,Science, pp. 1221-1225, vol. 299 (2003).
Kinnamon and Margolskee: “Mechanisms of taste transduction”Current Opinion in Neuriobiology6 506-513 (1996).
Lush, I. : “The genetics of tasting mice”Genet. Res. Camb. 53 95-99 (1989).
Matsunami and Buck.: “A Multigene Family Encoding a Diverse Array of Putative Pheromone Receptors in Mammals,”Cell90: 775-784 (Aug. 22, 1997).
McLaughlin et al.: “Gustducin is a taste-cell-specific G protein closely related to the transducins”Letters to Nature357 563-569 (Jun. 18, 1992).
Munzy, D. et al.; DatabaseGenEmbl; Accession No. AC006518, (May 1, 1999).
Naito et al.: “Putative pheromone receptors Ca2+- sensing receptor in Fugu,”Proc. Natl. Acad. Sci. 95: 5178-5181 (Apr. 1998).
Ryba and Tirindelli: “A New Multigene Family of Putative Pheromone Receptors,”Neuron19: 371-379 (Aug. 1997).
Skolnick and Fetrow, “From genes to protein structure and function: novel applications of computational approaches in the genomic era,”Trends in Biotech, vol. 18, pp. 34-39 (2000).
Smith and Zhang, “The challenges of genome sequence annotation or “The devil is in the details,”Nature Biotechnology, vol. 15, pp. 1222-1223 (1997).
Striem et al.: “Sweet tastants stimulate adenylate cyclase coupled to GTP-binding protein in rat tongue membranes,”Biochem260: 121-126 (1989).
Wamsley, et al. “Human BAC clone GS1-113H23 from 5p15.2, complete sequence”EMBL DatabaseEntry AC003015, Accession No. AC003015 (Oct. 31, 1997).
Wong et al.: “Transduction of bitter and sweet taste by gustducin”Letters to Nature381 796-800 (Jun. 27, 1996).
Adler Jon
Hoon Mark
Mueller Ken
Ryba Nick
Zuker Charles S.
Landsman Robert
Morgan & Lewis & Bockius, LLP
Parent Annette S.
The Regents of the University of California
LandOfFree
Methods for identifying modulators of SF taste receptor... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for identifying modulators of SF taste receptor..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for identifying modulators of SF taste receptor... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2644489