Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1994-11-30
1998-05-12
Campbell, Eggerton A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 721, C12Q 168, G01N 3353
Patent
active
057503397
ABSTRACT:
The invention features a method of distinguishing fetal cells from maternal cells in a sample. The method comprises the steps of contacting a sample comprising fetal cells and maternal cells with a probe which is complementary to HLA-G mRNA and identifying individual cells in which the probe hybridize to mRNA in the cells. The absence of hybridization indicates that the cells are maternal cells. The presence of hybridization indicates that the cells are fetal cells. Fetal cells identified in accordance with the invention may be tested for genetic abnormalities.
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Campbell Eggerton A.
Thomas Jefferson University
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