Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of regulating cell metabolism or physiology
Patent
1997-04-25
1999-12-14
LaGuyader, John L.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Method of regulating cell metabolism or physiology
435325, 435352, 435353, 435368, 435375, C12N 516
Patent
active
06001654&
ABSTRACT:
Method for producing a population of mammalian neurons and/or smooth muscle cells comprising contacting at least one mammalian neural stem cell with a culture medium containing one or more growth factors from the TGF-.beta. super family and detecting the differentiation of stem cell to a population of neurons or smooth muscle cells.
REFERENCES:
patent: 4705751 (1987-11-01), Mosher
patent: 4707448 (1987-11-01), Major
patent: 5061620 (1991-10-01), Tsukamota et al.
patent: 5087570 (1992-02-01), Weissman et al.
patent: 5411883 (1995-05-01), Bosset al.
Lo, L.-C., et al., "V-myc Immortalization of Early Rat Neural Crest Cells Yields a Clonal Cell Line Which Generates Both Glial and Adrenergic Progenitor Cells." Developmental Biology, 145:139-153 (1991).
Stemple, D.L., et al., "A Schwann Cell Antigen Recognized by Monoclonal Antibody 217c is the Rat Low-Affinity Nerve Growth Factor Receptor." Neuroscience Letters, 124:57-60 (1991).
Murphy, M., et al., "Generation of Sensory Neurons is Stimulated by Leukemia Inhibitory Factor." Proc. Natl. Acad. Sci. USA, 88:3498-3501 (1991).
Perris, R., et al., "Local Embryonic Matrices Determine Region-Specific Phenotypes in Neural Crest Cells." Science 241:86-89 (1988).
Morrison-Graham, K., et al., "Extracellular Matrix from Normal but Not Steel Mutant Mice Enhances Melanogenesis in Cultured Mouse Neural Crest Cells." Developmental Biology 139:299-307 (1990).
Boisseau, S., et al., "Mammalian Neuronal Differentiation: Early Expression of a Neuronal Phenotype from Mouse Neural Crest Cells in a Chemically Defined Culture Medium." Development 106:665-674 (1989).
Smith-Thomas, L.C., et al., "Expression of Schwann Cell Markers by Mammalian Neural Crest Cells in vitro" Development 105:251-262 (1989).
Deville, F.S.S.C., et al., "Developmental Potentialities of Cells Derived from the Truncal Neural Crest in Clonal Cultures." Developmental Brain Research 66:1-10 (1992).
Baroffio, A., et al., "Common Precursors for Neural and Mesectodermal Derivatives in the Cephalic Neural Crest." Development 112:301-305 (1991).
Baroffio, A., et al., "Common Precursors for Neural and Mesectodermal Derivatives in the Cephalic Neural Crest." Proc. Natl. Acad. Sci. USA 85:5325-5329 (1988).
Dupin, E., et al., "Schwann-Cell Differentiation in Clonal Cultures of the Neural Crest, as Evidenced by the Anti-Schwann Cell Myelin Protein Monoclonal Antibody." Proc. Natl. Acad. Sci. USA 87:1119-1123 (1990).
Cohen, A.M., et al., "A Clonal Approach to the Problem of Neural Crest Determination." Developmental Biology 46:262-280 (1975).
Sieber-Blum, M., et al., "Clonal Analysis of Quail Neural Crest Cells: they Are Pluripotent and Differentiate in Vitro in the Absence of Noncrest Cells." Developmental Biology 80:96-106 (1980).
Duff, R.S., et al., "In Vitro Clonal Analysis of Progenitor Cell Patterns in Dorsal Root and Sympathetic Ganglia of the Quail Embryo." Developmental Biology 147:451-459 (1991).
Bronner-Fraser, M., et al., "Developmental bPotential of Avian Trunk Neural Crest Cells In Situ." Neuron 3:755-766 (1989).
Bronner-Fraser, M., et al., "Cell Lineage Analysis Reveals Multipotency of Some Avian Neural Crest Cells." Nature 355:161-164 (1988).
Fraser, S.E., et al., "Migrating Neural Crest Cells in the Trunk of the Avian Embryo are Multipotent." Development 112:913-920 (1991).
Frank, E., et al., "Lineage of Neurons and Glia in Chick Dorsal Root Ganglia: Analysis in vivo with a Recombinant Retrovirus." Development 111:895-907 (1991).
Le Douarin, N.M., "Cell Line Segregation During Peripheral Nervous System Ontogeny," Science 231:1515-1522 (1986).
Gorham, J.D., et al., "The Expression of the Neuronal Intermediate Filament Protein Peripherin in the Rat Embryo." Developmental Brain Research 57:235-248 (1990).
Portier, M.M., et al., "Regulation of Peripherin in Mouse Neuroblastoma and Rat PC 12 Pheochroomocytoma Cell Lines." Dev. Neurosci. 6:215-226 (1983/1984).
Portier, M.M., et al., "Peripherin, a New Member of the Intermediate Filament (IF) Protein Family." Dev. Neurosci. 6:336-344 (1983/1984).
Parysek, L.M., et al., "Distribution of a Novel 57 kDa Intermediate Filament (IF) Protein in the Nervous System." The Journal Neuroscience 8:555:563 (1988).
Parysek, L.M., et al., "A Type III Intermediate Filament Gene Is Expressed in Mature Neurons." Neuron 1:395-401 (1988).
Anderson, D.J., et al., "A Bipotential Neuroendocrine Precursor Whose Choice of Cell Fate is Determined by NGF and Glucocorticoids." Cell 47:1079-1090 (1986).
Birren, S.J., et al., "A v-myc-Immortalized Sympathoadrenal Progenitor Cell Line in Which Neuronal Differentiation is Initiated by FGF but Not NGF." Neuron 4:189-201 (1990).
Potten, C.S., et al., "Stem Cells: Attributes, Cycles, Spirals, Pitfalls and Uncertainties Lessons for and From the Crypt." Development 110:1001-1020 (1990).
Hall, P.a., et al., "Stem Cells: The Generation and Maintenance of Cellular Diversity." Development 106:619-633 (1989).
Raff, M.C., et al., "A Glial Progenitor Cell that Develops in vitro into an Astrocyte or an Oligodendrocyte Depending on Culture Medium." Nature 303:390-396 (1983).
Jessen, K.R., et al., "Threee Markers of Adult Non-Myelin-Forming Schwann Cells, 217c(Ran-1), A5E3 and GFAP: Development and Regulation by Neuron-Schwann Cell Interactions." Development 109:91-103 (1990).
Reynolds, B.A., et al., "Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervious System." Science 255:1707-1710 (1992).
Porter, S., et al., "Schwann Cells Stimulated to Proliferate in the Absence of Neurons Retain Full Functional Capability." The Journal of Neuroscience 6:3070-3078 (1986).
Brockes, J.P., et al., "Studies on Cultured Rat Schwann Cells. I. Establishment of Purified Populations from Cultures of Peripheral Nerve." Brain Research 165:105-118 (1979).
Huzar, D., et al., "Migration and Proliferation of Cultured Neural Crest Cells in W Mutant Neural Crest Chimeras." Development 112:131-141 (1991).
Anderson, D.J., "The Neural Crest Cell Lineage Problem: Neuropoiesis." Neuron 3:1-12 (1989).
Dodd, J., et al., "Spatial Regulation of Axonal Glycoprotein Expression on Subsets of Embryonic Spinal Neurons." Neuron 1:105-116 (1988).
Ross, A.H., et al., "Characterization of Nerve Growth Factor REceptor in Neural Crest Tumors Using Monoclonal Antibodies." Proc. Natl. Acad. Sci. USA 81:6681-6685 (1984).
Johnson, D., et al., "Expression and Structure of the Human NGF Receptor." Cell 47:545-554 (1986).
Chandler, C.E., et al., "A Monoclonal Antibody Modulates the Interaction Nerve Growth Factor with PC12 Cells." The Journal of Biological Chemistry 259:6882-6889 (1984).
Chao, M.V., et al., "Gene Transfer and Molecular Cloning of the Human NGF Receptor." Science 232:518-521 (1986).
Radeke, M.J., et al., "Gene Transfer and Molecular Cloning of the Rat Nerve Growth Factor Receptor." Nature 325:593-597 (1987).
Weskanp, G., et al., "Evidene that Biological Activity of NGF is Mediated through a Novel Subclass of High Affinity Receptors." Neuron 6:649-663 (1991).
Lendahl, U., et al., "CNS Stem Cells Express a New Class of Intermediate Filament Protein." Cell 60:585-595 (1990).
Hockfield, S., et al., "Identificateion of Major Cell Classes in teh Developing Mammalian Nervous System." The Journal of Neuroscience 5:3310-3328 (1985).
Friedman, B., et al., "Monoclonal Antibody Rat 401 Recognizes Schwann Cells in Mature and Developing Peripheral Nerve." The Journal of Comparative Neurology 295:43-51 (1990).
Stemple, D., et al., "Isolation of a Stem Cell for Neurons and Glia from the Mammalian Neural Crest." Cell 71:973-985 (1992).
Reynolds, B.A., et al., "EGF- and TGFb-Responsive Striatal Embryonic Progenitor Cells Produce Both Neurons and Astrocytes." Soc. Neurosc. Abst., 15-1147 (1990).
Reynolds, B.A., et al., "A Non-Transformed, Growth Factor-Dependent Stem Cell Line Derived from the Embryonic Mouse CNS Produces Neurons, Astrocytes and Oligodendrocytes." Current Contents/Life Sciences, Excerpta Medica (EMBASE) and Neuroscience Abstracts 4(3):208 (1992).
Bartlett, P.F., et al., "Immortalization of mouse neural precursor cells by teh c-myc o
Anderson David J.
Shah Nirao M.
California Institute of Technology
Elrifi Ivor R.
LaGuyader John L.
Primce John T.
Shibuya Mark L.
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