Unsaturated hydroxyalkylquinoline acids as leukotriene antagonis

Details Unsaturated hydroxyalkylquinoline acids as leukotriene antagonis Unsaturated hydroxyalkylquinoline acids as leukotriene antagonis

1996-02-08

1999-01-05

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142242, 5142288, 5142305, 5142325, 514247, 514253, 514256, 514257, 514311, 514313, 514314, A61K 3154, A61N 4342, A61N 4354, A61N 4358

Patent

active

058563229

ABSTRACT:
Compounds having the formula I: ##STR1## are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.

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