Methods for determining whether to provide an inhibitor of...

Surgery – Diagnostic testing – Cardiovascular

Reexamination Certificate

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Reexamination Certificate

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07146205

ABSTRACT:
The present invention provides methods for determining whether to provide an inhibitor of sympathetic nervous system activity to a human being suffering from an autoimmune disease and/or fibromyalgia. The methods of this aspect of the invention each include the steps of: (a) measuring the heart rate variability of a human being suffering from an autoimmune disease or fibromyalgia, to yield heart rate variability data; (b) analyzing the heart rate variability data to determine whether there is excessive sympathetic nervous system activity in the heart of the human being; and (c) providing an inhibitor of sympathetic nervous system activity to the human being if there is excessive sympathetic nervous system activity in the heart of the human being.

REFERENCES:
patent: 6482163 (2002-11-01), Oka et al.
patent: 2002/0045835 (2002-04-01), Masakov et al.
patent: 2004/0210261 (2004-10-01), King et al.
Journal of Neurology, Neurosurgery and Psychiatry “Analysis of Heart Rate Variations in Patients with Multiple Sclerosis,” B. Neubauer et al, vol. 41, pp. 417-419, 1978.
Baevskiy, R.M., et al.,Mathematical Analysis of Changes in Heart Rate Rhythm Under Stress, Moscow Science, 1984.
Bellavere, F., “Heart Rate Variability in Patients With Diabetes and Other Noncardiological Diseases,” in Malik, M. and A.J. Camm (eds.),Heart Rate Variability, Futura Publishing Co., Ch. 38, pp. 507-516, 1995.
Cerutti, S., et al., “Spectral Analysis of the Heart Rate Variability Signal,” in Malik, M. and A.J. Camm (eds.),Heart Rate Variability, Futura Publishing Co., Ch. 5, pp. 63-74, 1995.
Elenkov, I.J., et al., “The Sympathetic Nerve-An Integrative Interface Between two Supersystems: The Brain and the Immune System,”Pharmacol. Rev. 52(4):595-638, 2000.
Hainsworth, R., “The Control and Physiological Importance of Heart Rate,” in Malik, M. and A.J. Camm (eds.),Heart Rate Variability, Futura Publishing Co., Ch. 1, pp. 3-19, 1995.
Kennedy, H.L., “Heart Rate Variability Instruments From Commercial Manufacturers,” in Malik, M. and A.J. Camm (eds.),Heart Rate Variability, Futura Publishing Co., Ch. 10, pp. 127-132, 1995.
Kleiger, R.E., et al., “Time-Domain Measurements of Variability,” in Malik, M. and A.J. Camm (eds.),Heart Rate Variability, Futura Publishing Co., Ch. 3, pp. 33-45, 1995.
Malik, M., “Geometrical Methods for Heart Rate Variability Assessment,” in Malik, M. and A.J. Camm (eds.),Heart Rate Variability, Futura Publishing Co., Ch. 4, pp. 47-61, 1995.
Martínez-Lavín, M., et al., “Circadian Studies of Autonomic Nervous Balance in Patients with Fibromyalgia,”Arthritis&Rheumatism 41(11):1966-1971, 1998.
McMillan, D.E., “Heart Rate Variability During Sleep in Fibromyalgia and Insomnia,” Doctoral Dissertation, University of Washington, pp. 1-79, 2001.
Nestler, E.J., et al., “Molecular Control ofLocus coeruleusNeurotransmission,”Biol. Psychiatry 46:1131-1139, 1999.
Petzke, F., et al., “Sympathetic Nervous System Function in Fibromyalgia,”Current Rheumatology Reports 2:116-123, 2000.
Raj, S.R., et al., “Dysautanomia Among Patients With fibromyalgia a Non-invasive Assessment,”Jour. of Rheumatol., 27(11):2660-2665, 2000.

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