Methods for buffer stabilized aqueous deacylation

Food or edible material: processes – compositions – and products – Products per se – or processes of preparing or treating... – Carbohydrate containing

Reexamination Certificate

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C426S548000, C536S124000, C536S127000

Reexamination Certificate

active

06890581

ABSTRACT:
The present invention relates to novel methods for stabilizing aqueous deacylation, via use of buffers in the production of sucralose. The present invention provides a process for producing sucralose from an acyl-sucralose compound whereby the acyl-sucralose compound is deacylated in the presence of a buffering agent, which stabilizes the pH of the feed mixture and decreases the accumulation of undesired anhydro compounds. Further, the present invention provides a process whereby the acyl-sucralose compound is deacylated directly either prior to or after removal of the tertiary amide reaction vehicle from the neutralized chlorination feed mixture. An aqueous solution of sucralose including salts and other compounds is produced, from which sucralose is recovered by extraction and purified by crystallization.

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International Search Report dated Aug. 25, 2003.

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