Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Reexamination Certificate
2007-04-10
2007-04-10
Vogel, Nancy (Department: 1636)
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
C424S423000
Reexamination Certificate
active
10276501
ABSTRACT:
The invention uses recombinant parvoviruses, and particularly recombinant adeno-associated virus (rAAV) to deliver genes and DNA sequences for gene therapy following manipulation of the therapeutic virus for packaging and transport. The invention delivers therapeutic viral vectors via rAAV affixed to support matrixes (i.e., sutures, surgically implantable materials, grafts, and the like).
REFERENCES:
patent: 5658785 (1997-08-01), Johnson
patent: 5869306 (1999-02-01), Kuma et al.
patent: 6333194 (2001-12-01), Levy et al.
patent: 2003/0053990 (2003-03-01), Rabinowitz et al.
patent: 2003/0108525 (2003-06-01), Sista et al.
patent: WO 94/29471 (1994-12-01), None
patent: WO 98/41240 (1998-09-01), None
patent: WO 00/41731 (2000-07-01), None
patent: WO 00/43044 (2000-07-01), None
patent: WO 01/09360 (2001-02-01), None
Siemens et al., J. Natl. Cancer Inst. vol. 92 No. 5, pp. 403-412 (2000).
Croyle et al. Pharmaceutical Development and Technology 3/3: 373-383 (1998).
Verma et al. Nature 389:239-242 (1997).
Palu et al. J. Biotechnol. 68:1-13 (1999).
Fox, ASM News , Feb. 2000, 66 (2): 1-3.
Monahan, et al., abstract, “Stability of recombinant adeno-associated virus vectors permits delivery on implantable matrices,”Blood, 96(11 Part I): 525a (2000).
Nybert-Hofman et al., “Instability of adenoviral vectors during transport and it's implication for clinical studies,”Nature Medicine3(4): 955957 (1999).
Siemens, et al.; “Viral Vector Delivery in Solid-State Vehicles: Gene Expression in a Murine Prostate Cancer Model,”Journal of National Cancer Institute, 92(5): 403-412 (2000).
Airu et al., “Molecular bypass, the application of VEGF to gene therapy of limb ischemia;”Natl Med J China; 76: 9; 662-665 (1996). (Abstract in English only; Chinese language document.).
Qin et al., “Gene suture—a novel method for intramuscular gene transfer and its application in hypertension therapy,”Life Sciences; 65: 21; 2193-2203 (1999).
Monahan Paul E.
Rabinowitz Joseph E.
Samulski Richard Jude
Myers Bigel Sibley and Sajovec, PA
The University of North Carolina at Chapel Hill
Vogel Nancy
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