Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Reexamination Certificate
2006-10-10
2006-10-10
Lankford, Jr., Leon B. (Department: 1651)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
C435S029000, C435S034000, C435S014000, C436S001000, C436S815000, C422S001000
Reexamination Certificate
active
07118857
ABSTRACT:
Methods and compositions for detection of microbial contaminants in peritoneal dialysis solutions are provided. The methods and compositions employ modified bioburden testing and the detection of peptidoglycan. A novel cause of aseptic peritonitis is provided—aseptic peritonitis associated with gram positive microbial contamination of a dialysis solution. Peptidoglycan is a major component of a gram positive bacterial cell wall and thus can serve as a marker for gram positive bacteria. In this regard, testing for peptidoglycans can be utilized to effectively prevent peritonitis in patients that use the peritoneal dialysis solutions, such as peritoneal dialysis solutions that contain a glucose polymer including an icodextrin and the like.
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Giertych Joseph A.
Kunzler Jacqueline A.
Martis Leo
Mongoven James W.
Owen, Jr. William F.
Barrett Robert
Basso Thomas
Baxter Healthcare S.A.
Baxter International Inc.
Ford Allison M.
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