Methods and compositions employing interferon-gamma

Details Methods and compositions employing interferon-gamma Methods and compositions employing interferon-gamma

1990-05-18

1992-07-21

Wax, Robert A.

Drug, bio-affecting and body treating compositions

Lymphokine

Interferon

530351, A61K 3766, C07K 1300

Patent

active

051321106

ABSTRACT:
The present invention is directed to improved pharmaceutical compositions employing interferon-gamma which have been treated to remove interferon-gamma inhibitory activity associated with such preparations. In addition, the present disclosure details treatment protocols, including the elevation of patient body temperature and the use of combined or sequential interferon-gamma treatments, to enhance interferon-gamma efficacy and reduce the resistance associated with interferon-alpha and/or beta therapy.

REFERENCES:
Kantarjian et al. (1987) Acta Haemat. 78 Supl 1, 70-74.
Robins (1984) Cancer Res (Suppl.)44, 48785-48835.
Heron et al (1978) Nature 274, 508-510.
Harai et al (1984) J. Interferon Res. 4, 507-516.
Gutterman et al (1984) Cancer Res 44, 4164-4171.
Groveman et al. (1984) Cancer Res 44, 5517-5521.
Yerushalmi et al. Biol. Abstract 74:19064, Proc. Soc. Exp. Biol. Med 169 413-415 (1982).

Affiliated with

Also associated with

Rating

Methods and compositions employing interferon-gamma does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and compositions employing interferon-gamma, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and compositions employing interferon-gamma will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-841906