Methods and active substances for protecting organs

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C514S002600, C514S006900, C435S001100, C435S001200, C530S380000, C530S392000, C530S395000, C530S416000, C530S417000, C530S422000, C530S830000, C530S831000

Reexamination Certificate

active

06924267

ABSTRACT:
The present invention comprises a method of protecting organs or tissue susceptible to reperfusion-induced dysfunction after ischemia. The method comprises parenterally administering to a patient a therapeutical composition containing natural alpha-1 acid glycoprotein, natural alpha-1 antitrypsin or a mixture thereof. Alternatively, organ or tissue transplants can be contacted with natural alpha-1 acid glycoprotein, natural alpha-antitrypsin or mixtures by perfusing or flushing them with a solution containing natural alpha-1 acid glycoprotein, natural alpha-1 antitrypsin or mixtures thereof in a concentration of 0.1 to 5 g/l.

REFERENCES:
patent: 2003/0069174 (2003-04-01), Pichler et al.
patent: WO 97/32893 (1997-09-01), None
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Pichler, et al., Preclinical investigatios of α1-acid glycoportein (orosomucoid), Wien Klin Wochenschr (the middle european journal of medicine) (1999) 111/5: 192-198.

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