Method to provide bacterial ghosts provided with antigens

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification

Reexamination Certificate

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C530S402000, C530S403000, C530S422000, C530S810000, C530S350000, C424S234100, C424S193100, C424S190100, C424S191100, C424S203100, C424S244100, C424S266100, C424S265100, C424S279100, C424S278100, C424S282100, C435S243000, C435S259000

Reexamination Certificate

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07067639

ABSTRACT:
Methods for improving binding of a proteinaceous substance to cell-wall material of a Gram-positive bacterium are disclosed. The proteinaceous substance includes an AcmA cell-wall binding domain, homolog or functional derivative thereof. The method includes treating the cell-wall material with a solution capable of removing a cell-wall component such as a protein, lipoteichoic acid or carbohydrate from the cell-wall material and contacting the proteinaceous substance with the cell-wall material.

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