Chemistry: analytical and immunological testing – Hemoglobin – myoglobin – or occult blood – Glycosylated hemoglobin
Patent
1993-05-03
1994-03-08
Housel, James C.
Chemistry: analytical and immunological testing
Hemoglobin, myoglobin, or occult blood
Glycosylated hemoglobin
436 15, 436 17, 436 18, 436161, 436175, 530417, G01N 3372, G01N 3004
Patent
active
052926630
ABSTRACT:
An eliminating agent used for the measurement of the amount of glycosylated hemoglobins in a blood sample is provided. The eliminating agent comprises condensed phosphoric acids and/or the salts thereof as the main ingredient, wherein the agent eliminates labile glycosylated hemoglobin A.sub.1c into non-glycosylated hemoglobin and glucose. There is also provided a reagent comprising the eliminating agent and a hemolysis agent, which is used for the measurement of the amount of glycosylated hemoglobins; and an eluent comprising the eliminating agent, which is used for the separation of glycosylated hemoglobins in blood samples by ion-exchange chromatography to measure the amount of the glycosylated hemoglobins. A method for measuring the amount of glycosylated hemoglobin A.sub.1c in a blood sample involves the use of the eliminating agent, the reagent comprising the eliminating agent and the hemolysis agent, and/or the eluent.
REFERENCES:
patent: 3689633 (1972-09-01), Matsushima et al.
patent: 3814820 (1974-06-01), Busta et al.
patent: 3864085 (1975-02-01), Woodbridge
patent: 4297238 (1981-10-01), Vormbrock et al.
patent: 4399227 (1983-08-01), Niederau et al.
patent: 4409335 (1983-10-01), Hanamoto et al.
patent: 4414305 (1983-11-01), Nakamura et al.
patent: 4876188 (1989-10-01), Smith et al.
patent: 4879039 (1989-11-01), Takahashi et al.
Vandegrift et al, Chemical Abstracts; vol. 95, Abstract No. 95:5371t, 1981.
W. Pschyrembel, "Klinisches Worterbuch", 254th edition, 1982, Walter de Gruyter, Berlin-New York, p. 446, entry titled Hamolyse (in vitro).
"Ullmanns Encyklopadie der technischen Chemie", 4th Edition, (1979) vol. 18, pp. 306-308.
D. E. Goldstein et al, Clin. Chem. (1986) 32:B64-B70.
Clinical Chemistry vol. 28, No. 3, 1982 pp. 512-515.
Chemical Abstracts, vol. 111, 23 Oct. 1989, p. 372, Abstract No. 150054v.
Kawabe Toshiki
Takechi Masahiro
Yamazaki Kazutoshi
Yokoi Masayuki
Housel James C.
Ludlow Jan M.
Sekisui Kagaku Kogyo Kabushiki Kaisha
LandOfFree
Method of treating blood containing labile glycosylated hemoglob does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of treating blood containing labile glycosylated hemoglob, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of treating blood containing labile glycosylated hemoglob will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-152676