Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Patent
1995-06-07
1999-11-02
Reeves, Julie
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
530351, 5303879, 53038823, 5303892, 5303911, 4241391, 4241451, 4241721, 424 851, 435 696, 435 7021, 435331, 435335, C07K 122, C07K 1452, C07K 1624, A61K 39395
Patent
active
059773235
ABSTRACT:
Two novel cytokines which are involved in an inflammatory response (inflammatory cytokines) are disclosed. The inflammatory cytokines have been isolated from activated peripheral blood, preferably monocytes adhered to plastic; or peripheral blood leukocytes induced with calcium ionophore and mezerin. The two cytokines are Gro .beta. and .gamma., and their cDNA and amino acid sequences are disclosed. The expression of the genes in various cells is presented. Assay and diagnostic utilities using the cytokines; recombinant materials and procedures; purification procedures; and monoclonal antibodies to the cytokines are also shown.
REFERENCES:
patent: 5154921 (1992-10-01), Sager
Trask et al 1990 J. Cell Biochem Supple. (14Part B) p. 5.
Sager et al 1990 Molecular & Cellular Biology of Cytokines 327-332.
TeKamp-Olson et al 1990 J. Exp. Med. 172: 911-919.
Harlow & Lane 1988 Antibodies: A Laboratory Manual Cold Spring Harbor Press Chapters 5,6,7 & 13.
Haskill John Stephen
Martin George
Nitecki Danute E.
Ralph Peter
Blackburn Robert P
Chiron Corporation
Chung Ling-Fong
Potter Jane E. R.
Reeves Julie
LandOfFree
Method of purifying Gro .beta. or Gro .alpha. protein using anti does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of purifying Gro .beta. or Gro .alpha. protein using anti, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of purifying Gro .beta. or Gro .alpha. protein using anti will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2137018