Method of producing rough strains of bacteria and uses thereof

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S253100

Reexamination Certificate

active

08071354

ABSTRACT:
The present invention relates to a method of producing rough strains of a bacterium, such asMycobacterium obuense, said method comprising exposing said bacterium to a sulfone and/or sulfonamide (such as 4,4′-Diaminodiphenyl sulfone or an analogue thereof). A rough strain ofMycobacterium obuenseproducible by said method and uses thereof. In particular, uses of a rough strain ofMycobacterium obuensedeposited under the Budapest Treaty at the NCTC with the accession number NCTC 13365.

REFERENCES:
patent: 5521300 (1996-05-01), Shah et al.
patent: 5525463 (1996-06-01), Zolg
patent: 5599545 (1997-02-01), Stanford et al.
patent: 5721209 (1998-02-01), Horwitz et al.
patent: 5786326 (1998-07-01), Horwitz
patent: 5994346 (1999-11-01), Horwitz et al.
patent: 6136529 (2000-10-01), Hammond
patent: 6218107 (2001-04-01), Brentano et al.
patent: 6408880 (2002-06-01), Kaul
patent: 6627203 (2003-09-01), Griffiths et al.
patent: 6900204 (2005-05-01), Michaelis et al.
patent: 7067500 (2006-06-01), Thornton
patent: 7078399 (2006-07-01), Michaelis et al.
patent: 7122525 (2006-10-01), Michaelis et al.
patent: 7252937 (2007-08-01), Kaltenboeck
patent: 2003/0104513 (2003-06-01), Thornton
patent: 2003/0105086 (2003-06-01), Michaelis et al.
patent: 2003/0219788 (2003-11-01), Kaltenboeck
patent: 2004/0014749 (2004-01-01), Michaelis et al.
patent: 2004/0014750 (2004-01-01), Michaelis et al.
patent: 2004/0034021 (2004-02-01), Michaelis et al.
patent: 2004/0037844 (2004-02-01), Rook et al.
patent: 2004/0063718 (2004-04-01), Michaelis et al.
patent: 2006/0013830 (2006-01-01), Bottasso et al.
patent: 1054055 (1979-05-01), None
patent: 0 556 284 (1997-06-01), None
patent: WO 91/02542 (1991-03-01), None
patent: WO 98/09985 (1998-03-01), None
patent: WO 02/32455 (2002-04-01), None
patent: WO 2004022093 (2004-03-01), None
patent: WO 2005/049056 (2005-06-01), None
Abbot N. C., et al., “Immunotherapy withMycobacterium vaccaeand peripheral blood flow in long-treated leprosy patients, a randomised, placebo-controlled trial,”European Journal of Vascular and Endovascular Surgery(2002) vol. 24 pp. 202-208.
Barrow, W., et al., “Isolation in high frequency of rough variants ofMycobacterium intracellularelacking c-mycoside glycopeptideollpid antigens,”Journal of Bacteriology(1982) vol. 150:1, pp. 381-384.
Bauer, M.E., et al., “Chronmic stress in caregivers of dementia patients is associated with reduced lymphocyte sensitivity to glucocrorticoids,”Journal of Neuroimmunology(2000) vol. 103, pp. 84-92.
Belisle, J., et al., “Chemical basis of rough and smooth variation of mycobacteria,”Journal of Bacteriology(1989) vol. 171:6, pp. 3465-3470.
Chambers, et al., “Association of bovine papillomavirus with the equine sarcoid,”Journal of General Virology(2003) vol. 84, pp. 1055-1062.
Choi, Inseon S., et al., “Therapeutic effects of BCG vaccination in adult asthmatic patients: a randomized, controlled trial,”Annals of Allergy, Asthma, and Immunology(2002) vol. 88 pp. 584-591.
Clerici, M., et al., “ATH1→TH2 switch is critical step in the etiology of HIV infection,”Immunology Today(1993) vol. 14:3, pp. 107-111.
Clerici, M., et al., Correlates of protection in HIV infection and the progression of HIV infection to AIDS,Immunology Letters(1996) vol. 51 pp. 69-73.
Crisp, Samantha, et al., “Antiendonthelial antibodies after heart transplantation: the accelerating factor in transplant-associated coronary artery disease?”The Journal of Heart and Lung Transplant(1994) p. 81-91.
de Roos, N. M., et al., “Effects of probiotic bacteria on diarrhoea, lipid metabolism, and carcinogenesis; a review of papers published between 1988 and 1998,”Am. J. Clinc. Nutr(2000) vol. 71 pp. 405-411.
Elenkov I. J., et al., “Stress hormones, Th1/Th2 patterns, pro/anti-inlammatory cytokines and susceptibility to disease,”Trends Endocrininol Metab(1999) vol. 10:9 pp. 359-368.
Elenkov, I. J., et al. “Stress, cytokine patterns and susceptibility to disease,”Baillière's Clinical Endocrinology Metabolism(1999) vol. 13:4, pp. 583-595.
Faist, E., et al., “Update on the mechanisms of immune suppression of injury and immune modulation,”World Journal of Surgery(1996) vol. 20:3, pp. 454-459.
George, Jacob, et al., “Requisite role for interleukin-4 in the acceleration of fatty streaks induced by heat shock protein 65 orMycobacterium tuberculosis,” America Heart Association(2000) pp. 1203-1210.
Gill, H.S., et al. “Enhancement of immunity in the elderly by dietary supplementation with the probioticBifidobacterium lacticHN0191-3,”Am. J. Clin. Nutr. (2001) vol. 74:6 pp. 833-839.
Gill, H.S., et al., “Dietary probiotic supplementation enhances natural killer cells activity in the elderly: an investigation of age-related immunological changes,”Journal of Clinical Immunology(2001) vol. 21:4, pp. 264-271.
Ginaldi L., et al., “The immune system in the elderly: innate immunity,”Immunologic Research(1999) vol. 20:2 pp. 117-126.
Goronzy, J. J., et al., “Value of Immunological markers in prdicting responsiveness to Influenza vaccination in elderly individuals,”Journal of Virology(2001) vol. 75:24 pp. 12182-12187.
Iwakabe K, et al., “The restraint stress drives a shift in Th1/Th2 balance towards Th2-dominant immunity in mice,”Immunology Letters(1998) vol. 62, pp. 39-43.
Johnson, A., Daniel, et al., “Effect of heat shock proteins on survival of isolated aortic cells from normal and atherosclerotic cynomolgus macaques,”Atherosclerosis(1990) vol. 84, pp. 111-119.
Kang, D. H., et al., “TH1 and TH2 cytokine responses to academic stress,”Research in Nursing&Health(2001) vol. 24, pp. 245-257.
Kansal, R., et al., “Change in colony morphology influences the virulence as well as the biochemical properties pf theMycobacterium aviumcomplex,”Microbial Pathogenesis(1998) vol. 25, pp. 203-214.
Kim, J.H, et al., “Induction of oral tolerance to Japanese cedar pollen,”Arch Pharm Res(2001) vol. 24:6, pp. 557-563.
Lawrence, K. D., “Central/peripheral nervous system and immune response,”Toxicology(2000) vol. 124, pp. 189-201.
Lio, Domenico., et al., “In vitro treatment with interleukin-2 normalizes type-1 cytokine production by lymphocytes from elderly,”Immunopharmacology and Immunotoxicology(2000) vol. 22:2, pp. 195-203.
Manabe, YC, et al., “Naturally attenuated orally administeredMycobacterium microtias a tuberculosis vaccine is better than subcultaneousMycobacterium bovisBCG,”Infection and Immunity(2002) vol. 70:3 pp. 1566-1570.
Maraveyas, A., et al., “Possible improved survival of patients with stage IV AJCC melanoma receiving SRL 172 immunotherapy: correlation with induction of increased levels of intracellular interleukin-2 in peripheral blood lymphocytes,”Annals of Oncology(1999) vol. 10 pp. 817-824.
Mehta, S. K., et al., “Epstein-Barr virus reactivation associated with diminished cell-mediated immunity in Antarctic expeditioners,”Journal Medical Virology(2000) vol. 61 pp. 235-240.
Mukherjee, et al., “Association of antibodies to heat-shock protein-65 with percutanteous tramsluminal coronary angioplasty and subsequent restenosis,” Thrombois and Haemostasis (1996) vol. 75 pp. 258-260.
Norbiato, G., et al., “Microbial and fungal contamination contributes to physical stress in space flight: studies in the Euromir-95 mission,” J. Garvit Physiol (1998) vol. 5:1, p. 145-6.
Paik, In-ho, et al., “Psychological stress may induce increased humoral and decreased cellular immunity,” Behavioral Medicine (2000) vol. 26:3, pp. 139-141.
Prinzis, S., et al., “Search for the molecular basis of morphological varariation inMycobacterium avium,” Infection and Immunity(1994) vol. 62:5 pp. 1946-1951.
Sanders, M.E., et al., “Invited review: the scientific basis ofLactobacill

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of producing rough strains of bacteria and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of producing rough strains of bacteria and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of producing rough strains of bacteria and uses thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4264035

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.