Method of producing...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

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06897322

ABSTRACT:
The invention relates to a method of preparing 1-alkyl-3-aryl-5-difluoromethoxy-1H-pyrazoles of the formula (I), wherein aryl represents a mono- or polysubstituted phenyl ring, and R1represents C1-C4alkyl. The inventive method is characterized by reacting, in a first reaction step, a β-ketoester of the general formula (II) with hydrazine and by successively reacting the reaction product obtained with chlorodifluoromethane and a compound R1-L, wherein R1has the meanings indicated above and L represents the leaving group of a nucleophilic displacement reaction.

REFERENCES:
patent: 361 114 (1990-04-01), None
patent: 443 059 (1991-08-01), None
patent: 0443059 (1990-02-01), None
patent: WO9519967 (1995-01-01), None
Auwers,J.Prakt.Chem.,vol. 110,1925, 204-234.
Chem. Soc.of Japan, Bull.Chem.Soc.,vol. 54,3221-3222(1981) Kagaruki et al.
J.Prakt.Chem.vol. 52, 1895,23-57, Rothenburg.
Justus LiebigsAnn.Chem.vol. 352, 1907,163-193 Michaelis.
91-136056 Derwent Abst.
92-320741 Derwent Abst.
94-269416 Derwent Abst.
98-019962 Derwent Abst.

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