Method of preparing an undifferentiated cell

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

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C435S373000, C435S374000, C435S377000

Reexamination Certificate

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10140978

ABSTRACT:
Disclosed is a method of preparing an undifferentiated cell. The method includes contacting a more committed cell with an agent that causes the more committed cell to retrodifferentiate into an undifferentiated cell.

REFERENCES:
patent: 5004681 (1991-04-01), Boyse et al.
patent: 5843780 (1998-12-01), Thomson
patent: 6200806 (2001-03-01), Thomson
patent: 6227202 (2001-05-01), Matapurkar
Clark (Protein Engineering of Antibody Molecules for Prophylactic and Therapeutic Applications in Man, 1993, p. 1).
Reinherz et al (PNAS, 1982, vol. 79, pp. 6047-6051).
Pettersen et al, (Journal of Immunology, 1998, vol. 160, pp. 4343-4352).
Genestier et al (Blood, 1997, vol. 90, pp. 3626-3639).
Genestier et al (Blood, 1997, vol. 90, pp. 726-735).
Woodle et al, (Journal of Immunology, 1997, vol. 158, pp. 2156-2164).
Vidovic and Toral (Cancer Letter, 1998, vol. 128, pp. 127-135) t.
Thibeault et al (Cellular Immunology, 1999, vol. 192, pp. 79-85).
Berto et al (Journal of Immunology, 2000, vol. 164, pp. 2379-2385).
Tawara et al (Blood, 2001, vol. 98, pp. 250-B).
Ulloa-Montoya et al, Journal of Bioscience and Bioengineering, vol. 100, pp. 12-27.
Miller et al (Biochimica et Biophysica Acta, 2005 vol. 1756, pp. 25-52).
(Hug, Medicina (Kaunas), 2005, vol. 41, pp. 1002-1010).
Paul, Fundamental Immunology (textbook), 1993, pp. 15-16.
Cornwell, J., “A Matter of Your Life and Death,”The Sunday Times Magazine, Feb. 1, 2004.
Abuljadayel, I.S., “Induction of Stem Cell-Like Plasticity in Mononuclear Cells Derived from Unmobilised Adult Human Peripheral Blood,”Current Medical Research and Opinion, 19(5): 355-375, 2003.
Abuljadayel, I.S. et al., “SCID Repopulating Cells Derived from Unmobilised Adult Human Peripheral Blood,”Current Medical Research and Opinion, 20(1): 87-100, 2004.
Scripps Research Institute Press Release, “Regenerative Chemical Turns Muscle Cells into Stem Cells, Say Scientists at the Scripps Research Institute”, Dec. 22, 2003.
Boral et al. Blood Preservation in Transfusion Medicine, pp. 938-846. in Henry, J., ed., Clinical Diagnosis and Management by Laboratory Methods, 18th ed., W.B. Saunders Company, Philadelphia, 1991.
Uriel, J., “Cancer, Retrodifferentiation, and the Myth of Faust”, Cancer Research 36, 4269-4275, 1976. Sato et al., Blood, 82(12):3600-3609, Dec. 1993.
Nelson et al., “Basic Examination of Blood”, pp. 553-603 in Clinical Diagnosis & Management By Laboratory Methods, Henry, J.B. ed., W.B. Saunders Company, Philadelphia, 1991.
Nelson et al., “Hematopoiesis”, pp. 604-626, in Clinical Diagnosis & Management By Laboratory Methods, Henry, J.B., ed., W.B. Saunders Company, Philadelphia, 1991.
Ogawa et al., “Renewal and Committment to Differentiation of Hemopoietic Stem Cells (An Interpretive Review)”, Blood, vol. 61, No. 5, pp. 823-829, May 1983.
The Molecular Control of Cell Division, Differentiation Committment and Maturation in Haemopoietic Cells, vol. 339, pp. 27-30, May 1989.
Jordan et al., “Cellular and Development Properties of Fetal Hemapoietic Stem Cells”, pp. 953-963, Cell, vol. 61, Jun. 1990.
Spangrude et al., “Purification and Characterization of Mouse Hematopoietic Stem Cells”, Science, vol. 241, pp. 58-62, Jul. 1988.
Orlic et al., What Defines a Pluripotent Hematopoietic Stem Cell (PHSC): Would the Real PHSC Please Stand Up?, Blood, vol. 84, No. 12, pp. 3991-3994, Dec. 1994.
Moore et al., “Clinical Implications of Positive and Negative Hematopoietic Stem Cell Regulators”, Blood, vol. 78, pp. 1-19, Jul. 1991.
Moorehead, P.S., “Human Blood Leukocytes”, pp. 58-61, in Tissue Culture, ed. Kruse et al., Academic Press, New York, 1973.
Stedman's Medical Dictionary, 24th ed., p. 1352, Williams & Wilkens, Baltimore, 1982.
Nelson et al., “Hematopoiesis”, pp. 604-605, in Henry, J., ed., Clinical Diagnosis and Management by Laboratory Methods, 18th ed., W.B. Saunders Company, Philadelphia, 1991.
Hass, R., “Retrodifferentiation—an alternative biological pathway in human leukemia cells”, European Journal of Cell Biology, 58:1-11, 1992.
Altomonte, M., et al., “Cross-Linking of HLA Class II Antigens Modulates the Release of Tumor Necrosis Factor-.alpha. by the EBV-B Lymphoblastoid Cell Line JY,” The Journal of Immunology (151(10):5115-5122.
Cambier, J.C., et al., “Molecular Mechanisms of Transmembrane Signaling in B Lymphocytes,” in Ann Rev Imm. (1987) 5:175-199.
Cambier, J.C., et al., “Ia-Mediated Signal Transduction Leads to Proliferation of Primed B Lymphocytes,” J Exp Med (1989) 170:877-886.
Clement, L.T., et al., “Antibodies Reactive with Class II Antigens Encoded for by the Major Histocompatibility Complex inhibit human B Cell Activation,” The Journal of Immunology (1986) 136(7):2375-2381.
Deeg, H.J., et al., “Major histocompatibility complex class II molecules, hemopoiesis and the marrow microenvironment,” Bone Marrow Transplantation (1993) 12:425-430.
Ghaderi, A.A., et al., “Cross-linking of a sequential epitope within the .alpha.-chain of HLA-DR/DP molecules suppressing B lymphocyte growth and inducing homotypic cell aggregation,” Immunology Letters (1994) 39:113-119.
Hajeer, A.H., et al., “Antibodies to major histocompatibility complex class II inhibit proliferation, but increase production of soluble CD23 in lymphoblastoid B-cell lines,” Immunology (1993) 80:593-597.
Huss, R., et al., “Major Histocompatibility Complex Class II Expression is Required for Posttransplant Immunological but not for Hemopoietic Reconstitution in Mice,” Transplantation (1994) 58(12):1366-1371.
Huss, R., et al., “Differentiation of canine bone marrow cells with hemopoietic characteristics from an adherent stromal cell precursor,” Proc Natl Acad Sci USA (1995) 92:748-752.
Mooney, N., et al., “HLA Class-II Antigen-Mediated Induction of a Proliferative Response to Anti-IgM in Human B Lymphocytes,” Int J Cancer (1991) Supplement 6:30-33.
Mooney, N.A., et al., “Bacterial Superantigen Signaling via HLA Class II on Human B Lymphocytes,” Molecular Immunology (1994) 31(9):675-681.
Morio, T., et al., “Engagement of MHC class II molecules by staphylococcal superantigens activates src-type protein tyrosine kinases,” Eur J Immunol (1994) 24:651-658.
Naitoh, K., et al., “Signal Transmission through MHC Class II Molecules in a Human B Lymphoid Progenitor Cell Line: Different Signaling Pathways Depending on the Maturational Stages of B Cells,” Microbiol Immunol (1994) 38(12):967-976.
Newell, M.K., et al., “Ligation of major histocompatibility complex class II molecules mediates apoptotic cell death in resting B lymphocytes,” Proc Natl Acad Sci USA (1993) 90(Nov.):10459-10463.
Perl, A., et al., “Rearrangement of the T-Cell Receptor Alpha, Beta and Gamma Chain Genes in Chronic Lymphocytic Leukemia,” Leukemia Research (1990) 14(2):131-137.
Scholl, P.R., et al., “MHC class II signaling in B-cell activation,” Immunology Today (1994) 15(9):418-422.
Takahama, Y., et al., “Disparate functions of I-A and I-E molecules on B cells as evidenced by the inhibition with anti-I-A and anti-I-E antibodies of polyclonal B cell activation,” Eur J Immunol (1989) 19:2227-2235.
Truman, J-P., et al., “Lymphocyte programmed cell death is mediated via HLA class II DR,” International Immunology (1994) 6(6):887-896.
Wade, W.F., et al., “Structural compartmentalization of MHC class II signaling function,” Immunology Today (1993) 14(11):539-546.
J. Uriel; Cancer Research 36, 4269-4275; Nov. 1976; Cancer, Retrodifferentiation, and the Myth of Faust.
M. Fukuda; Cancer Research, 41; 4621-4628; Nov. 1981; Tumor-producing Phorbol Diester-induced specific changes in Cell Surface Glycoprotein Profile of K562 Human Leukemic Cells.
N.J. Curtin, et al.; Br. J. Cancer (1983) 48;

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