Method of preparing 2'-O-methyl cytidine monomers useful in olig

Details Method of preparing 2'-O-methyl cytidine monomers useful in olig Method of preparing 2'-O-methyl cytidine monomers useful in olig

1992-06-03

1997-02-25

Sayala, Chhaya D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 281, 536 284, 544317, C07H 1906, C07H 19067, C07H 19073

Patent

active

056060491

ABSTRACT:
Methods of preparing N.sup.4 -alkanoyl, aroyl and aralkanoyl 2'-O-methylcytidine derivatives are provided. Also provided are novel cytidine derivatives and nucleoside monomers comprising these cytidine derivatives which are useful in the synthesis of Oligomers, including oligonucleotides and methylphosphonate Oligomers.

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