Method of multiplexed analysis using ion mobility spectrometer

Radiant energy – Ionic separation or analysis – Methods

Reexamination Certificate

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C250S287000

Reexamination Certificate

active

07541576

ABSTRACT:
A method for analyzing analytes from a sample introduced into a Spectrometer by generating a pseudo random sequence of a modulation bins, organizing each modulation bin as a series of submodulation bins, thereby forming an extended pseudo random sequence of submodulation bins, releasing the analytes in a series of analyte packets into a Spectrometer, thereby generating an unknown original ion signal vector, detecting the analytes at a detector, and characterizing the sample using the plurality of analyte signal subvectors. The method is advantageously applied to an Ion Mobility Spectrometer, and an Ion Mobility Spectrometer interfaced with a Time of Flight Mass Spectrometer.

REFERENCES:
patent: 5396065 (1995-03-01), Myerholtz et al.
patent: 6300626 (2001-10-01), Brock et al.
patent: 2005/0001163 (2005-01-01), Belov et al.
patent: 2006/0054804 (2006-03-01), Wexler

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