Method of measuring enzymatic activity using novel peptide deriv

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase

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G01N 3114

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active

041918096

ABSTRACT:
The compound 7-glycylprolylamino-4-methylcoumarin and certain of its derivatives are utilized for the diagnosis of pathological conditions such as hepatic diseases and gastric cancer by measuring the enzymatic activity of X-prolyl dipeptidyl-aminopeptidase.

REFERENCES:
patent: 4028318 (1977-06-01), Aurell et al.
patent: 4056519 (1977-11-01), Bobbitt et al.
patent: 4070245 (1978-01-01), Svendsen
Hino et al., Clin. Chim. Acta., 62 (1975), 5-11.
Bergmeyer, Methods of Enzymatic Analysis, vol. 2, Academic Press, Inc., New York, 1974, pp. 950-953.

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