Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1993-07-06
1995-01-03
Henley, III, Raymond J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514547, 514550, 514551, 514562, 514824, A61K 3700, A61K 31225, A61K 3122, A61K 31195
Patent
active
053786920
ABSTRACT:
A method of lowering lipids is disclosed wherein a patient is administered a lipid metabolism improving composition characterized by comprising a compound of the following formula: ##STR1## wherein R.sub.1 represents a hydrogen atom or a lower alkyl group; R.sub.2 and R.sub.3 are the same or different and each represents a hydroxyl group, a lower alkoxy group or an amino group, or a pharmacologically acceptable salt thereof as an active ingredient.
Since the compound of the present invention lowers blood triglyceride, cholesterol and .beta.-lipoprotein levels, it is of value for ameliorating hyperlipidemia in arteriosclerotic diseases, e.g. myocardinal infarction, angina pectoris, cerebral infarction, cerebral arteriosclerosis, etc., nephrosis, hypertension, diabetes, obesity and other diseases, and prevention of various circulatory diseases.
REFERENCES:
patent: 5081149 (1992-01-01), Ohmori et al.
patent: 5135952 (1992-08-01), Ohmori et al.
patent: 5212159 (1993-05-01), Ohmori et al.
patent: 5232913 (1993-08-01), Ohmori et al.
Isowaki Yuuichi
Ogata Kazumi
Ohmori Shinji
Sakaue Takahiro
Tsuruoka Hideki
Henley III Raymond J.
Senju Pharmaceutical Co. Ltd.
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