Method of large scale growth of toxoplasmic microorganisms

Details Method of large scale growth of toxoplasmic microorganisms Method of large scale growth of toxoplasmic microorganisms

1987-11-13

1989-04-25

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Lymphokine

424 11, 424 93, 4352521, 436536, A61K 39002, G01N 3354

Patent

active

048246662

ABSTRACT:
A method of producing large scale growth of parasites of the genus Toxoplasma is disclosed which comprises inoculating the microorganisms into a non-adherent human cell line, such as a monocytoid lymphoma cell line, and maintaining the cell line in tissue culture media capable of supporting the growth of the microorgranism while the cell line is being maintained. This large scale production allows for the development of vaccines for Toxoplasma microorganisms which previously have been hard to grow in the numbers needed to readily prepare vaccines, and allows for more rapid antibody detection procedures with regard to these microorganisms. There are also disclosed methods for preparing such vaccines, and methods for carrying out antibody detection assays.

REFERENCES:
patent: 4473548 (1984-09-01), Frenkel et al.
patent: 4473549 (1984-09-01), Frenkel et al.
patent: 4480043 (1984-10-01), Trouyez
patent: 4564592 (1986-01-01), Gaafar et al.
ATCC, Catalogue of Cell Lines & Hybridomas, ATCC CRL 1593, U-937 (Human hiocytic lymphoma), p. 139, 5th edition, 1985.

Affiliated with

Also associated with

Rating

Method of large scale growth of toxoplasmic microorganisms does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of large scale growth of toxoplasmic microorganisms, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of large scale growth of toxoplasmic microorganisms will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1194851