Method of increasing solubility of enzymes

Details Method of increasing solubility of enzymes Method of increasing solubility of enzymes

1985-04-29

1988-04-19

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435183, 435219, 435212, 435213, 435226, 435227, 435229, 435230, 435816, 435220, C12N 956, C12N 900, C12N 950, C12N 954, C12N 952

Patent

active

047389257

ABSTRACT:
A method is provided for increasing the solubility of an enzyme in an aqueous solution comprising providing a water-soluble anionic surfactant to the solution and further providing the solution with a pH above that which result in the formation of an enzyme/surfactant precipitate. The application is further directed to an aqueous solution containing an anionic surfactant and having an enzyme concentration contained therein which is higher than that possible in the absence of the surfactant.

REFERENCES:
patent: 4144130 (1979-03-01), Kula et al.
patent: 4515705 (1985-05-01), Moeddel
Biochemistry, vol. 12, No. 13, 1973, pp. 2525-2530.

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