Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of culturing cells in suspension
Patent
1998-10-26
2000-08-01
Redding, David A.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Method of culturing cells in suspension
435395, 4352867, 4353033, 4353041, 366219, C12M 302
Patent
active
060965444
ABSTRACT:
A method for enhancing the mixing of materials in a roller bottle by the introduction of controlled axial and cross-sectional flow perturbations is disclosed. The effectiveness of the method is demonstrated by achieving higher efficiency in cell culturing and virus propagation in roller bottles by introducing controlled flow perturbations during the process.
REFERENCES:
patent: 3091435 (1963-05-01), Pease
patent: 3682080 (1972-08-01), Merz
patent: 3705544 (1972-12-01), Ratowsky
patent: 3981488 (1976-09-01), Ratowsky
patent: 3982259 (1976-09-01), Van Baerle
patent: 4373029 (1983-02-01), Nees
patent: 5153133 (1992-10-01), Schwarz et al.
J.R. Archer, International PDA Meeting, pp. 17-21, (Feb. 1991).
J.H. Hughes, Clinical Microbiology Reviews, vol. 6(2), pp. 150-175 (Apr. 1993).
R.M. Gallegos Gallegos, et al., Archives of Medical Research, vol. 26(1), pp. 59-63, (1995).
J.H. Hughes, et al., Journal of Virological Methods, vol. 22 pp. 75-80 (1988).
V.G. Edy, Adv. Exp. Med. Biol., vol. 172, pp. 169-178, (1984).
H. Kotani, et al., Human Gene Therapy, vol. 5, pp. 19-28, (1994).
R. Kunitake, et al., Journal of Biotechnology, vol. 52, pp. 289-294, (1997).
B.J. Montagnon, Tropical and Geographical Medicine, vol. 37(3), pp. S40-41, (Sep. 1985).
E. Rivera, et al., Research Veterinary Science, vol. 41, pp. 391-396, (Nov. 1986).
A.Y. Elliott, "Nonpurfused Attachment Systems for Cell Cultivation", pp. 207-216 (A.S. Lubiniecki, Ed, "Large Scale Mammalian Cell Culture Technology", Marcel Dekker (1990)).
J.L. Melnick, et al., Prop. Soc. Exp. Biol. Med., vol. 81, pp. 208-213, (1952).
E.I. Tsao, et al., Annals NY Acad. of Science, vol. 665, pp. 127-136, (1992).
G.A. Zimmermann, et al., Journal of Immunology, vol. 134(3), pp. 1866-1874, (Mar. 1985).
J. Novotny, et al., Acta Virol., vol. 36, pp. 483-487, (1992).
W.R. Earle, et al., Annals NY Acad. of Science, vol. 58, pp. 1000-1011, (1954).
M.A. Sturgill, et al., Journal of Clinical Microbiology, vol. 27(3), pp. 577-579, (1989).
Bramble Joye L.
Muzzio Fernando J.
Searles James A.
Camara Valerie J.
Daniel Mark R.
Merck & Co. , Inc.
Redding David A.
Rutgers The State University of New Jersey
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