Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Attached to antibody or antibody fragment or immunoglobulin;...
Patent
1993-02-16
1995-07-11
Parr, Margaret
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Attached to antibody or antibody fragment or immunoglobulin;...
436501, 436536, 436548, 435 723, 5303888, 5303913, A61K 4300, A61K 4900, A61K 3514, G01N 33566
Patent
active
054318971
ABSTRACT:
This invention provides a method of imaging a colorectal carcinoma lesion in a human patient which comprises administering to the patient a monoclonal antibody capable of binding to a cell surface antigen associated with the colorectal carcinoma lesion and which is labeled with an imaging agent under conditions so as to form a complex between the monoclonal antibody and the cell surface antigen, imaging any complex so formed, and thereby imaging the colorectal carcinoma lesion.
This invention also provides a monoclonal antibody designated AS 33 (ATCC Accession No. HB 8779) and the hybridoma which produces it.
REFERENCES:
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Pimm, N. V. Behring Inst. Mitt. May, 1984, (74) 80-6 Abstract only.
Kirkegaard & Perry Labratories, Inc. Catalog.
Divgi Chaitanya R.
Oettgen Herbert F.
Old Lloyd J.
Real Francisco X.
Sakamoto Jun-ichi
Parr Margaret
Sisson Bradley Lounsbury
Sloan-Kettering Institute for Cancer Research
White John P.
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