Method of determining antibiotics in biological liquids

Details Method of determining antibiotics in biological liquids Method of determining antibiotics in biological liquids

1983-08-10

1986-02-04

Rosen, Sam

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

435 32, 435231, C12Q 134

Patent

active

045686378

ABSTRACT:
The presence of beta lactam ring-containing cephalosporins and penicillin is determined in biological liquids such as milk by contacting the test liquid with a beta lactam ring-containing chromogenic compound (such as nitrocefin) and penicillinase and measuring the color developed in the test liquid in comparison with a color standard.

REFERENCES:
patent: 3063916 (1962-11-01), Kosikowski
patent: 3126325 (1964-03-01), Poole
patent: 3644177 (1972-02-01), Zyk
patent: 3830700 (1974-08-01), O'Callaghan et al.
patent: 4239745 (1980-12-01), Charm
patent: 4448880 (1984-05-01), Schindler et al.
Voller et al., Journal of Clinical Pathology 1978, vol. 31, pp. 507-520.
Thornsberry et al., Antimicrobial Agents and Chemotherapy, Nov. 1974, vol. 6, No. 5, pp. 653-654.
O'Callaghan et al., Antimicrobial Agents and Chemotherapy 1972, vol. 1, No. 4, pp. 283-288.
Rosenblatt et al., American Journal of Clinical Pathology, 1978, pp. 351-354.

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