Method of and test kit for mutagenesis testing

Details Method of and test kit for mutagenesis testing Method of and test kit for mutagenesis testing

1996-07-25

1998-10-06

Ketter, James

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Testing efficacy or toxicity of a compound or composition

435 6, 435 29, 4351723, 435325, 435352, 435353, 435354, A61K 4900

Patent

active

058172904

ABSTRACT:
A novel method and test kit for mutagenesis testing applicable to an organism or a cell.

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patent: 5602300 (1997-02-01), Gossen et al.
Adhya, S.L. and J.A. Shapiro "The Galactose Operon of E. Coli K-12. I. Structural and Pleiotropic Mutations of the Operon" Genetics 62:231-247 (Jun. 1969).
Albertini, R.J. et al. "In Vivo Somatic Mutations in Humans: Measurement and Analysis" Annu. Rev. Genet. 24:305-326 (1990).
Boerrigter, M.E.T.I. et al. "Plasmid-based transgenic mouse model for studying in vivo mutations" Nature 377:657-659 (19 Oct. 1995).
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Gossen, J.A. and J. Vijg "E coli C: a convenient host strain for rescue of highly methylated DNA" Nucleic Acids Research 16(19):9343.
Gossen, J.A. et al. "Application of galactose-sensitive E. coli strains as selective hosts for LacZ.sup.- plasmids" Nucleic Acids Research 20(12):3254.
Gossen, J.A. et al. "Plasmid Rescue from Transgenic Mouse DNA Using Lacl Repressor Protein Conjugated to Magnetic Beads" BioTechniques 14(4):624-629 (1993).
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