Thiazole derivatives, processes for production thereof and pharm

Details Thiazole derivatives, processes for production thereof and pharm Thiazole derivatives, processes for production thereof and pharm

1993-07-13

1994-11-29

Shaw, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514274, 514336, 514362, 514363, 514369, 544316, 544319, 544405, 546280, 548135, 548184, 548185, A61K 31505, A61K 3144, A61K 3141, A61K 31425

Patent

active

053691075

ABSTRACT:
Compounds of the formula: ##STR1## wherein A is S, SO, or SO.sub.2, R.sup.1 is H or acyl, R.sup.2 is H, alkyl, hydroxyalkyl, halogen or carboxy, and R.sup.3 is pyridyl are claimed. The compounds are useful as therapeutic agents for the treatment of e.g. rheumatism, nephritis and thrombocytopenia.

REFERENCES:
patent: 4649146 (1987-03-01), Takaya et al.
patent: 4735957 (1988-04-01), Takaya et al.
patent: 4921887 (1990-05-01), Matsuo et al.
patent: 5256675 (1993-10-01), Matsuo et al.
Gibbs et al., "Sulfur Derivatives of Thiazoles" Chemical Society Journal, (1945) pp. 925-926.
Claub et al., ".beta.-Lactame mit uber Heteroatomegebundenen Substituenten" (1974) Liebigs Annalen Chemi., 539.
M. Ohta et al., Chemical Abstracts 45:7111g (1951).

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