Method for treating cancer

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C536S004100, C536S055000, C536S118000, C435S184000

Reexamination Certificate

active

07148200

ABSTRACT:
A method for treating a cancer. The cancer excluding an adenocarcinoma and being epithelioma, glioma, sarcoma, melanoma, lymphoma or leukemia; or the cancer is an adenocarcinoma cancer excluding colon cancer, lung cancer and gastric cancer. The method comprises administering to a subject in need thereof and suffering from cancer, a pharmaceutically effective amount of at least one sulfoquinovosylacylglycerol compound represented by formula (1):wherein R101represents an acyl residue of an unsaturated fatty acid and R102represents a hydrogen atom and/or at least one pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 5489578 (1996-02-01), Rosen et al.
patent: 5695752 (1997-12-01), Rosen et al.
patent: 5783693 (1998-07-01), Bertozzi et al.
patent: 6395886 (2002-05-01), Yamazaki et al.
patent: 6444795 (2002-09-01), Yamazaki et al.
patent: 6518248 (2003-02-01), Yamazaki et al.
patent: 6518410 (2003-02-01), Yamazaki et al.
patent: 6770629 (2004-08-01), Yamazaki et al.
patent: 2002/0022597 (2002-02-01), Yamazaki et al.
patent: 2002/0028776 (2002-03-01), Yamazaki et al.
patent: 2002/0028777 (2002-03-01), Yamazaki et al.
patent: 2002/0052327 (2002-05-01), Yamazaki et al.
patent: 2002/0173471 (2002-11-01), Yamazaki et al.
patent: 55-130996 (1980-10-01), None
patent: 03-052815 (1991-03-01), None
patent: 3-52816 (1991-03-01), None
patent: 03-052816 (1991-03-01), None
patent: 3-66603 (1991-03-01), None
patent: 03-066603 (1991-03-01), None
patent: 60-040159 (1991-09-01), None
patent: 03-246203 (1991-11-01), None
patent: 7-242691 (1995-09-01), None
patent: 9-268198 (1997-10-01), None
patent: 11-106395 (1999-04-01), None
patent: 11-106395 (1999-04-01), None
patent: 2000-143516 (2000-05-01), None
patent: WO 91/02521 (1991-03-01), None
patent: WO 97/40838 (1997-11-01), None
patent: WO 00/53190 (2000-09-01), None
Peer et al., “Synthesis of an L-Fucose-Derived Cyclic Nitrone and its Conversion to α-L-Fucosidase Inhibitors,”Helvetica Chemica Acta, 82(7), 1044-1065 (Jul. 7, 1999).
Sanders et al., “Synthesis of Sulfated Trisaccharide Ligands for the Selectins,”Tetrahedron, 53(48), 16391-16422 (Dec. 1, 1997).
Arasappan et al., “Regiospecific 4, 6-Functionalization of Pyranosides via Dimethylboron Bromide-Mediated Cleavage of Phthalide Orthoesters,”J.American Chemical Society, 117(1), 177-183 (Jan. 11, 1995).
Thiem et al., “Synthesen von Methyl-4-O-(β-D-curaocsyl)-α-D-curamicosid, dem Glycosid der Disaccharideinheit E-F von Flambamycin und Isomeren,”Justus Liebig's Annalen der Chemie, 1987(4), 289-295 (Apr. 1987).
Fujimaki et al., “Conversion of 1, 6-Anhydromaltose into Pseudodisaccharides Containing Aminocyclitols as Constituent,”Agricultural&Biological Chemistry, 44(9), 2055-2059 (Sep. 1980).
Tulloch et al., “Combination and Positional Distribution of Fatty Acids in Plant Sulfolipids,”Hoppe-Seyler's Zeitschrift Physiol. Chem., 354, 879-889 (Aug. 1973).
Fusetani et al., “Structures of Two Water Soluble Hemolysins Isolated from the Green AlgaUlva pertusa,” Agricultural and Biological Chemistry, 39(10), 2021-2025 (Oct. 1975).
Kitagawa et al., “Sulfoglycolipid from Sea UrchinAnthocidaris vrassisspinaA. Agassiz,”Chemical&Pharmaceutical Bulletin, 27(8), 1934-1937 (Aug. 1979).
Gustafson et al., “AIDS-Antiviral Sulfolipids From Cyanobacteria (Blue-Green Algae),”J. National Cancer Institute(USA), 81(16), 1255-1258 (Aug. 16, 1989).
Adebodun et al., “Spectroscopic Studies of Lipids and Biological Membranes: Carbon-13 and Proton Magic-Angle Sample-Spinning Nuclear Magnetic Resonance Study of Glycolipid-Water Systems,”Biochemistry, 31(18), 4502-4509 (May 1992).
Gage et al., “Comparison of Sulfoquinovosyl Diacylglycerol from Spinach and the Purple BacteriumRhodobacter sphaeroidesby Fast Atom Bombardment Tandem Mass Spectrometry,”Lipids, 27(8), 632-636 (Aug. 1992).
Morimoto et al., “Studies on Glycolipids. VII. Isolation of Two New Sulfoquinovosyl Diacylgycerols from the Green AlgaChlorella vulgaris,” Chemical&Pharmaceutical Bulletin, 41(9), 1545-1548 (Sep. 1993).
Amarquaye et al., “A New Glycolipid fromByrsonima crassifolia,” Planta Medica, 60(1), 85-86 (Feb. 1994).
Murakami et al., “Enzymatic Transformation of Glyceroglycolipids intosn- 1 andsn- 2 Lysoglyceroglycolipids by Use ofRhizopus arrhizusLipase,”Tetrahedron, 50(7), 1993-2002 (Feb. 14, 1994).
Vishwanath et al., “Interaction of Plant Lipids with 14 kDa Phospholipase A2Enzymes,”Biochemical Journal, 320(1), 93-99 (Nov. 15, 1996).
Golik et al., Isolation and Structure Determination of Sulfonoquinovosyl Dipalmitoyl Glyceride, a P-Selectin Receptor Inhibitor from the AlgaDictyochloris Frangrans, Journal of Natural Products, 60(4), 387-389 (Apr. 1997).
Vasänge et al., “A Sulfonoglycolipids from the FernPolypodium decumanumand its Effect on the Platelet Activating-factor Receptor in Human Neutrophils,”Journal of Pharmaceutical Pharmacology, 49(5), 562-566 (May 1997).
Kim et al., “Structural Identification of Glycerolipid Molecular Species Isolated from CyanobacteriumSynechocytissp. PCC 6803 Using Fast Atom Bombardment Tandem Mass Spectrometry,”Analytical Biochemistry, 267, 260-270 (1999).
Mizushina et al., “Search and Structural Identification of Inhibitory Substance on DNA Polymerase of Higher Organisms,” published inA Collection of Summaries of Lectures at Convention of Natural Organic Compounds, published by Prof. K. Sakai (Kyushu University) and the Organizing Committee of the 40th Symposium on the Chemistry of Natural Products, Fukuoka, Japan, Aug. 31, 1998, only pp. 493-498 supplied.
H Nakane & K Ono, “Inhibitor of DNA Polymerase Activity,”Metabolism, 28(12), 1027-1034 (1991).
Pugh et al. (eds.),Stedman's Medical Dictionmary, 27the Ed.), Lippincott, Williams and Wilkins, Philadelphia, PA, 2000, only p. 24 supplied.
Mizushina, Yoshiyuki, et al., “Studies on Inhibitors of Mammalian DNA Polymerase alpha and beta,” Biochemistry Pharmacology, 55, 537-541 (1998).
Akio Ogana et al., Sulfated Glycoglycerolipid from Archaebacterium Inhibits Eukaryotic DNA Polymerase α, β and Retroviral Reverse Transcriptase and Affects Methyl Methanesulfonate Cytotoxicity,International Journal of Cancer, 76, 512-518 (1998).
Gerhard Kretzschmar et al., “Short Synthesis of Sulfatide- and SQDG-Mimetics as Small Molecular Weight Selectin inhibitors”,Tetrahedron, 54, 15189-15198 (1998).
Bernd Meyer et al., Syntheses of Benzyl 6-O-Sulfo-β-D-glucopyranoside Salts and Their 6S-Deuterated Analogues. Conformational Preferences of Their (Sulfonyloxy)methyl Group,Journal of Organic Chemistry, 55, 902-906 (1990).
Byeng Wha Son; “Glycolipids fromGracularia verrucosa”, Phytochemistry, vol. 29, No. 1, 1990; pp. 307-309.
Shirahashi Hideaki et al.; “Isolation and Identification of Anti-tumor-Promoting Principles from the Fresh-Water CyanobacteriumPhormidium tenus”, Chem. Pharm. Bull., vol. 41, No. 9, (1993) pp. 1664-1666, (Sep. 1993).
Morimoto, Takashi et al.; “Studies on Glycolipids. VII. Isolation of Two New Sulfoquinovosyl Diacylglycerols from the Green AlgaChlorella vulgaris”, Chem. Pharm. Bull. vol. 41,No. 9, 1993; pp. 1545-1548, (Sep. 1993).
Michael Keusgen et al.; “Sulfoquinovosyl Diacylglycerols from the AlgaHeterosigma carterase”, Lipids, vol. 32,No. 10; 1997; pp. 1101-1102.
Luca Rastrelli et al., “Glycolipids fromByrsonima crassifolia”; Phytochemistry, vol. 45, No. 4, 1997; pp. 647-650.
Sahara,H. et al.; “In vivo anti-tumour effect of 3′-sulfoquinovosyl-1′-monoacylglyceride isolated from sea urchin (Stronglyocentrotus intermedius) interstine”; British Journal of Cancer, vol. 75,No. 3, 1997; pp. 324-332.
Ohta, Keisuke et al.; “Sulfoquinovosyldiacylglycerol, KM043, a New Potent Inhibitor of Eukaryotic DNA Polymeraes and HIV-Revers

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