Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1991-09-05
1993-04-27
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514256, 514402, 514636, A61K 3155, A61K 31505, A61K 31415, A61K 31155
Patent
active
052062368
ABSTRACT:
A method for treating malaria which comprises to an afflicted host patient a therapeutically effective amount of a compound have the structure of formula I: ##STR1## wherein X is O or NH; R.sub.1 is H or two R.sub.1 groups on the same amidine group together represents --(CH.sub.2).sub.m --, wherein m=2, 3 or 4; R.sub.2 is H, NH.sub.2, Cl, NO.sub.2 ; R.sub.3 is H, CH.sub.3 or CH.sub.2 CH.sub.3 and n=2-6 or a pharmaceutically acceptable salt thereof provided that when X is O, both R.sub.2 and both R.sub.3 can not be H.
REFERENCES:
patent: 2277861 (1942-03-01), Ewins et al.
patent: 4546113 (1985-10-01), Glazer
patent: 4933347 (1990-06-01), Tidwell et al.
patent: 4963589 (1990-10-01), Tidwell et al.
Medicine, vol. 27, p. 359 (1948).
Chemical Abstracts, 96: 134342u (1982), [E. Steck et al., Exp. Parasitol. 1981, 52(3), 404-13].
Chemical Abstracts, 99: 63892g (1983), [L. Schmidt, Am. J. Trop. Med. Hyg., 1983, 32(2), 231-57].
Chemical Abstracts, 102: 40705g (1985).
Chemical Abstracts, 71: 20824r (1969).
Chemical Abstracts, 83: 22394x (1975).
Chemical Abstracts, 86: 106191d (1977).
Chemical Abstracts 87: 134731u (1977).
Peters et al., Annals of Tropical Medicine and Parasitology, 1975, 69(3) 311-328.
J. N. Ashley et al., Journal of the Chemical Society, 1942, 103-116.
Chemical Abstracts 78: 72150g (1973).
Geratz J. Dieter
Grogl Max
Hall James E.
Kyle Dennis E.
Ohemeng Kwasi A.
Drehkoff W. Dennis
Goldberg Jerome D.
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