Method for the preparation of medicinal capsules

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Polymer from ethylenic monomers only

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424 36, 424359, A61J 307, A61K 948

Patent

active

039432386

ABSTRACT:
A method for the preparation of gelatin capsules having a good disintegrating property, in which a material selected from the group consisting of a protein, an amino acid, a substance having at least one amino group, an antioxidant, monobasic sodium phosphate, and the mixture thereof is added to the encapsulated contents.

REFERENCES:
patent: 650760 (1900-05-01), Metcalf
patent: 671804 (1901-04-01), Metcalf
patent: 2990333 (1961-06-01), Graham
patent: 3456051 (1969-07-01), Mima et al.
patent: 3493652 (1970-02-01), Hartman
patent: 3639259 (1972-02-01), Scarpelli
Newton et al., J. Pharm. Pharmac. 23:452-453 (1971) "The Effect of Additives on the Release of Drug From Hard Gelatin Capsules."
Awe et al., Chem. Abst., 54:1801f(1960) "Formaldehyde-Casein As Tablet Disintegrant".
Tudermann et al., Chem. Abst., 55:2017a (1961) "Formaldehyde-Casein As Tablet Disintegrator".

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