Method for the preparation of fluticasone and related...

Organic compounds -- part of the class 532-570 series – Organic compounds – Cyclopentanohydrophenanthrene ring system containing

Reexamination Certificate

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C552S559000

Reexamination Certificate

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10847846

ABSTRACT:
This invention discloses a novel method for the conversion of carboxylic acids to carbothioic acids and application of the method to the preparation of androstane carbothiolates, such as fluticasone propionate, which avoids column chromatography.

REFERENCES:
patent: 4188385 (1980-02-01), Edwards
patent: 4198403 (1980-04-01), Alvarez
patent: 4263289 (1981-04-01), Edwards
patent: 4335121 (1982-06-01), Phillipps et al.
patent: 4578221 (1986-03-01), Phillipps et al.
patent: 6406718 (2002-06-01), Cooper
patent: 6747163 (2004-06-01), Rubinsztain et al.
patent: 2088877 (1982-06-01), None
patent: 2137206 (1984-10-01), None
patent: 109656 (1998-01-01), None
Phillipps et al, J. Med. Chem. 1994, 37, 3717-3729.
Karteez et al. (DN 105:6673, HCAPLUS, J. of Organic Chemistry (1986), 51(12), 2315-28).
Journal of Medicinal Chemistry, vol. 37, No. 22 1994, pp. 1276-1278.
Journal of Organic Chemistry, vol. 23, No. 8, 1958, p. 1277.
Journal of The American Chemical Society, vol. 108 No. 3, 1986, pp. 452-461.
Journal of The Chemical Society, Chemical Communications, No. 19, 1989, pp. 1435-1436.
Bull. Chem. Soc. Jpn 50(11):3071 (1977).
J. Ind. Chem. Soc. 52:150 (1977).
J. Org. Chem. 31:3980 (1966).
Org. Syn. Collective vol. VI:824 (1988).
J. Am. Chem. Soc. 69:2682 (1947).
Synlett. 11:1054 (1996).
J. Med. Chem. 37(22):3171 (1994).
J. Org. Chem. 51(12):2315 (1986).
Tetrahedron 36(4):539 (1980).
Chem. Ber. 113(5):1898 (1980).
Justus Liebigs Ann. Chem. 590:123 (1954).

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