Method for the diagnosis of virulent bacteria

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 737, 435 792, 435 795, 435 29, 435 32, 435 34, 530412, 530825, G01N 33569, C07K 314, C12Q 102

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053806484

ABSTRACT:
Induction of virulence related proteins in virulent pathogenic E. coli and Shigella by growing such bacteria in the presence of Congo Red as induction triggering factor, and the application of the induction for purposes of diagnosing virulent pathogens and their antibiotic sensitivity.

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Qadri et al. "Congo Red Binding and Salt Aggregation as Indicators of Viradence in Shijella Species" Jo. Clin. Micro. vol. 26 No. 7 Jul. 1988 pp. 1343-1348.
Hale et al. "Identification and Antigenic Characterization of Virulence Associated, Plasmid-Coated Proteins of Shijella spp. and Enteroinasive E. coli" Infect. & Immun. vol. 50, No. 3 Dec. '85 pp. 620-629.
Hale et al. "Characterization of Virulence Plasmids and Plasmid-Associated Outer Membrane Proteins in Shigella Flexerni, Shigella Sonnei and E. coli" Infect and Immun. vol. 40, No. 1 Apr. '83 pp. 340-350.
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Infection and Immunity, vol. 55, No. 6, 1987, Panagiotis A. Daskaleros et al: "Congo Red Binding Phenotype Is Associated with Hemin Binding and Increased Infectivity of Shigella flexneri in the HeLa Cell Model", pp. 1393-1398.
Infectiion and Immunity, vol. 54, No. 2, 1986, Panagiotis A. Daskaleros et al: "Characterization of Shigella flexneri Sequences Encoding Congo Red Binding (crb): Conservation of Multiple crb Sequences and Role of ISI in Loss of the Crb+ Phenotype", pp. 435-443.
Infection and Immunity, vol. 51, No. 2, 1986, Takashi Sakai et al: "Molecular Cloning of a Genetic Determinant for Conga Red Binding Ability Which Is Essential for the Virulence of Shigella".

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