Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure
Patent
1975-07-23
1977-11-15
Sebastian, Leland A.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Molecular bilayer structure
424 15, 424 12, 2523011R, A61K 4300
Patent
active
RE0294748
ABSTRACT:
A process comprising contacting particles of water insoluble polymers to which have been bound antibodies, by means of covalent bonds, against the protein or polypeptide to be determined, wherein a certain quantity of the protein or polypeptide is labeled with a radioactive isotope, whereupon the particles, subsequent to the reaction between the protein or the polypeptide and the antibodies attached to the particles are separated from the sample liquid and the radioactivity of the particle material and/or in the liquid is determined.
REFERENCES:
patent: 2770602 (1956-11-01), Weichelbaum
patent: 2911338 (1959-11-01), Tabern et al.
Munoz, John J., Some Newer Immunological Techniques, Analytical Chemistry, vol. 31, No. 6, pp. 981-985, June 1959.
Pressman et al., Computer Programs for Paired and Triad Radioiodine Label Techniques, Chem. Abstracts, vol. 64, p. 5606G, 1966.
Bennington, Radioautographic Analysis of Soluble Antibody-Antigen Complexes, Chem. Abstracts, vol. 54, p. 17521A.
Jagendorf et al., Biochem. Biophys. Acta, vol. 78, pp. 516 to 528 (1963).
Drizlikh et al., Biokhimiya, vol. 29, No. 6, pp. 1054 to 1062 (1964).
Axen Rolf E. A. V.
Porath Jerker O.
Wide Leif Edvin
Pharmacia AB
Sebastian Leland A.
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