Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Patent
1994-08-16
1997-04-22
Wax, Robert A.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
530413, 530418, 530420, 530421, 455 691, 455183, 455219, 455221, C07K 114, C07K 130, C07K 132, C07K 136
Patent
active
056230591
ABSTRACT:
A process for the microbial production of a protein susceptible to inactivation in a fluid production medium by continuously and reversibly protecting said protein against said inactivation during the production stage, separating the protein from the production medium, deprotecting the protein, and recovering the protein product. The process is especially useful for obtaining substantially increased yields of the protein in question by continuously precipitating said protein.
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Joergensen Per L.
Mikkelsen Jan M.
Nielsen Torben K.
Pedersen Poul E.
Petersen Joergen
Lambiris, Esq. Elias J.
Moore William W.
Novo Nordisk A S
Wax Robert A.
Zelson Esq. Steve T.
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