Method for producing an optically active 2,2-dimethylcyclopropan

Details Method for producing an optically active 2,2-dimethylcyclopropan Method for producing an optically active 2,2-dimethylcyclopropan

1983-04-05

1985-09-17

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562506, C07B 1900

Patent

active

045422354

ABSTRACT:
A method for producing an optically active 2,2-dimethylcyclopropanecarboxylic acid useful as an intermediate for dehydropeptidase I inhibitors, medicines and agricultural chemicals, which comprises reacting an optically active diphenylethylamine represented by the formula, ##STR1## wherein R.sub.1 and R.sub.2 are each a hydrogen atom or a lower alkyl group, with 2,2-dimethylcyclopropanecarboxylic acid in a solvent to achieve the optical purification of said acid.

REFERENCES:
patent: 4236026 (1980-11-01), Naumann
patent: 4257976 (1981-03-01), Pavan et al.
patent: 4337352 (1982-06-01), Naumann

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