Method for preparing finasteride

Details Method for preparing finasteride Method for preparing finasteride

1995-03-16

1997-09-23

Skane, Christine

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 61, C07D22118

Patent

active

056706430

ABSTRACT:
The present invention relates to a process for the preparation of finasteride, the compound of formula (I), comprising the reaction of the compound of formula (II) with t-butylamine. ##STR1##

REFERENCES:
patent: 4377584 (1983-03-01), Rasmusson
patent: 4760071 (1988-07-01), Rasmusson
patent: 5468860 (1995-11-01), Dolling et al.
patent: 5571817 (1996-11-01), Rasmusson et al.
G. H. Rasmusson, et al., "Steroids: Structure-Activity Relationships for Inhibition of 5.alpha.-Reductase Androgen Receptor Binding," J. Med.Chem., 29, pp. 2298-2315, 1986 no month available.

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