Method for positively detecting toxic material

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving oxidoreductase

Reexamination Certificate

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Reexamination Certificate

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07981634

ABSTRACT:
Disclosed herein is a method of positively detecting toxic materials within a sample, the method including contacting sub-mitochondrial particles with an electron donor. The electron donor is reacted with an electron transfer system of the sub-mitochondrial particles to produce a reactant. A pH indicator has its pH adjusted to be in a range of 9 to 11. The pH indicator is added to each reactant. Color changes in the pH indicator permit the detection of toxins present in the sample.

REFERENCES:
patent: 4808517 (1989-02-01), Blondin et al.
patent: 5278048 (1994-01-01), Parce et al.
patent: 5372784 (1994-12-01), Morris et al.
patent: 5843696 (1998-12-01), Read et al.
patent: 2007/0231919 (2007-10-01), Choi et al.
Kurup C. et al. The Energy Linked Nature of Respiration Dependent Bromothymol Blue Color Decrease in Submitochondrial Particles. Biochim Biophys Acta 189 300-303, 1969.
Galkin A. et al. H+/2e− Stoichiometry in NADH Quinone Reductase Reactions Catalyzed by Bovine Heart Submitochondrial Particles. FEBS Letters 451 157-161, 1999.
Argese E. et al. Quantitative Structure Activity Relationships for theToxicity of Chlorophenols to Mammalian Submitochondrial Particles. Chemosphere 38(10)2281-2292, 1999.
European Search Report; EP06124019; Mar. 19, 2007. All referenced cited in the Search Report and not previously submitted are listed in this IDS.
H+2/e stoichiometry in NADH-quinone reductase reactions catalyzed by bovine heart submitochondrial particles; A.S. Galkin, V.G. Grivennikova, A.D. Vinogradov; BEBS Letters 451 (1999) pp. 157-161.
XP-002417263; The energy-linked nature of respiration-dependent bromothymol blue color decrease in submitochondrial particles; Biochim. Biophy. Acta, 189 (1969) pp. 300-303.
XP-002417265; WPI/Thomas; 1994; pp. 1.
XP009075526; Use of Submitochondrial Particles for Prediction of Chemical Toxicity in Man; L.M. Knobeloch, G.A. Blondin, and J.M. Harkin; Bull. Envirion. Contam, Toxicol. (1990) 44:661-668.
Phenolic Toxicity Detection and Classification Through the Use of a Recombinant BioluminescentEscherichia coli; Sue Hyung Choi, Man Bock Gu; Environmental Toxicology and Chemistry, vol. 20, No. 2, pp. 248-255, 2001.

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