Method for making insulin precursors and insulin precursor...

Details Method for making insulin precursors and insulin precursor... Method for making insulin precursors and insulin precursor...

2004-07-19

2008-05-27

Gupta, Anish (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S004300, C530S303000, C530S305000, C530S324000, C930S010000

Reexamination Certificate

active

07378390

ABSTRACT:
Novel insulin precursors and insulin precursor analogs comprising a connecting peptide (mini C-peptide) of preferably up to 15 amino acid residues and comprising at least one Gly are provided. The precursors can be converted into human insulin or a human insulin analog. The precursors will typically have a distance between B27 (atom CG2) and A1 (atom CA) of less than 5 Å.

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GenBank Accession #P01311.
GenBank Accession #I48166.
GenBank Accession #INOS.
GenBank Accession #INHY.
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