Method for making antiparasitic agents

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435 76, 435119, 4351721, 4352535, 43525235, 435886, 536 71, 549 9, 549 13, 549 58, C12P 1914, C07H 1708, C07D33500

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051127466

ABSTRACT:
Antiparasitic compounds of formula (I): ##STR1## The broken line at the 22-23 position representing an optional double bond and either R.sup.1 is H or OH and the double bond is absent or the double bond is present and R.sup.1 is absent; R.sup.2 is optionally substituted phenyl, or a group of formula (II): ##STR2## wherein X is O, S or --CH.sub.2 --, abc and d are 0-2 and a+b+c+d.ltoreq.5 R.sup.3 is H or Me

REFERENCES:
patent: 4328335 (1982-05-01), Mrozik
patent: 4423209 (1983-12-01), Mrozik
Cane, D. E. et al., J. Amer. Chem. Soc. vol. 109, 1255-1257 (1987).
Hutchinson, R. C. et al., J. Amer. Chem. Soc. 109, 1253-1255 (1987).
Meinwald, J. et al., J. Amer. Chem. Soc. 85, 582-585 (1963).
Robinson, J. A. et al., J. Chem. Soc., Chem. Comm. 1988, 4.
Yue et al., J. Am. Chem. Soc., vol. 109, 1987, pp. 1253-1255.

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