Drug – bio-affecting and body treating compositions – Lymphokine – Interleukin
Patent
1990-10-05
1992-07-21
Wax, Robert A.
Drug, bio-affecting and body treating compositions
Lymphokine
Interleukin
424 851, 514 8, 530351, A61K 4505, C07K 1300
Patent
active
051321092
ABSTRACT:
A method for inhibiting production of IgE, and a method for enhancing production of IgG are taught. The methods are linked to the role of interleukin 9 in antibody production. Specifically, production of IgG is potentiated by administering either to a subject or a cell culture a combination of interleukin 4 and interleukin 9. Production of IgE is inhibited by administering an amount of an interleukin 9 inhibitor to a subject.
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Braquet Pierre
Druez Catherine
Dugas Bernard
Mencia-Huerta Jean M.
Renauld Jean-Christophe
Departemente d'Immunologie Institut Henri Beaufour
Ekstrom Richard C.
Ludwig Institute for Cancer Research
Wax Robert A.
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