Method for identifying individuals suffering from a cellular abn

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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424 9371, 435 2, 435 71, 435 723, 435 72, 435325, 4353723, 435183, 435189, 436503, 436501, 436813, G01N 3353, G01N 33566, G01N 33567, C12N 508

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057472718

ABSTRACT:
The invention relates to the identification of complexes of HLA-A2 and tyrosinase derived peptides on the surfaces of abnormal cells. The therapeutic and diagnostic ramifications of this observation are the subject of the invention.

REFERENCES:
Dermer, Bio/Technology, vol. 12, p. 320, 1994.
Boon, Int. J. Cancer, vol. 54, pp. 177-180, 1993.
Hodes, "Chapter 20", from: Fundamental Immunology, Second Edition, Ed. W.E. Paul. Raven Press, 1989, pp. 606 and 618.

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