Method for identifying anti-parasitic compounds

Details Method for identifying anti-parasitic compounds Method for identifying anti-parasitic compounds

1993-10-29

1996-01-09

Fleisher, Mindy B.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Isomerase

514 12, 530350, A61K 3816, C07K 14435, C12N 990

Patent

active

054828503

ABSTRACT:
The present invention relates to the use of these cyclophilins, hereinafter referred to as "cyclophilin-like proteins (CLP)", in a method for identifying compounds capable of binding to and/or inhibiting the enzymatic activity of these proteins. Such compounds may be further screened for their ability to inhibit parasites which are not susceptible to the anti-parasitic effects of CsA.

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