Chemistry: analytical and immunological testing – Involving producing or treating antigen or hapten – Producing labeled antigens
Patent
1978-12-26
1983-02-01
Fagelson, Anna P.
Chemistry: analytical and immunological testing
Involving producing or treating antigen or hapten
Producing labeled antigens
260112R, 424 15, 424 85, 424 88, 424177, 424180, 435 7, 436827, 436548, G01N 3350, C07H 100, C12P 100, C12P 2100, C12Q 100
Patent
active
043715150
ABSTRACT:
A lectin is covalently bonded to an immunological conjugate such as an antibody-antigen or its equivalent. Then, the lectin-conjugate is isolated from the reaction product mixture by one of a number of alternative techniques involving one or more of the following types of reaction; (1) reversible reaction of the lectin with an insolubilized sugar to isolate lectin from the remainder of the mixture, (2) reaction of one immunological component (e.g., antibody) bonded to the lectin with an insolubilized corresponding component (e.g., antigen) to separate the antibody components from the remainder of the reaction mixture, and (3) filtration of the reaction components to separate on the basis of product molecular weight, size and/or shape of the components.
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E-Y Laboratories, Inc.
Fagelson Anna P.
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