Radioimmunoassay of pterins and novel pterin derivatives useful

Details Radioimmunoassay of pterins and novel pterin derivatives useful Radioimmunoassay of pterins and novel pterin derivatives useful

1980-07-07

1983-02-01

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

544258, 436538, 436540, 436542, G01N 3356, G01N 3358, C07D47500

Patent

active

043715141

ABSTRACT:
Pterin derivatives are described having the formula (I) ##STR1## wherein R represents a hydroxyphenyl group, a radioiodinated hydroxyphenyl group, a tyraminocarbonyl group, a radioiodinated tyraminocarbonyl group, a proteinocarbonyl group or a carboxy group; Q represents a straight or branched chain alkylene group having 1 to 6 carbon atoms; and R.sub.6 and R.sub.7 each represents a hydrogen, an alkyl group having from 1 to 6 carbon atoms, a hydroxyalkyl group having from 1 to 6 carbon atoms; and a radioimmunoassay method is described using a radioiodinated 4-hydroxy-2-tyraminopteridine derivative or a radioiodinated 4-hydroxy-2-tyraminocarbonylalkylaminopteridine derivative as the tracer.

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patent: 4146602 (1979-03-01), Gutcho et al.
patent: 4202976 (1980-05-01), Bayly et al.
patent: 4276280 (1981-06-01), Akerkar et al.

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