Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-10-16
2000-10-03
Achutamurthy, Ponnathapu
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352521, 435212, 530331, C12P 2106, C12N 948, C12N 112, A61K 3806
Patent
active
061271446
ABSTRACT:
An aminopeptidase inhibitor is used when expressing heterologous protein in a bacterial host, such as Streptomyces. Use of such an inhibitor inhibits degradation of the heterologous protein by aminopeptidases. Inhibitors are designed based upon the mechanism and substrate specificity of the target protease and expressed protein.
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Bartfeld Daniel
Butler Michael J.
Garven Sheila
Hadary Dany
Jenish David L.
Achutamurthy Ponnathapu
Cangene Corporation
Tung Peter P.
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