Para-nitrophenylalkylamines and pharmaceutical compositions

Details Para-nitrophenylalkylamines and pharmaceutical compositions Para-nitrophenylalkylamines and pharmaceutical compositions

1979-12-10

1981-07-07

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

564374, A61K 31135, C07C 8729

Patent

active

042775019

ABSTRACT:
Certain secondary and tertiary para-nitrophenylalkylamines are potent antiarrhythmic agents which prolong the action potential duration of cardiac tissue. A method of treating re-entrant arrhythmias, and pharmaceutical formulations containing para-nitrophenylalkylamines, are provided.

REFERENCES:
patent: 3639476 (1972-02-01), Eberle et al.
patent: 3759997 (1973-09-01), Napolitano
patent: 4219568 (1980-08-01), Goldberg et al.
Chem. Abst. 7, 344, (1913), Brawn et al.
Chem. Abst. 54,19588(f-i), (1960)-Morikawa.
Chem. Abst. 88, 50076(s), (1978)-Mutai et al.
Barlow et al.-Pharmac., (1969), 37, pp. 555-584.

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