Chemistry: analytical and immunological testing – Hemoglobin – myoglobin – or occult blood – Glycosylated hemoglobin
Patent
1982-05-28
1983-10-11
Marantz, Sidney
Chemistry: analytical and immunological testing
Hemoglobin, myoglobin, or occult blood
Glycosylated hemoglobin
210656, 422 61, 436 95, G01N 3366, G01N 3372
Patent
active
044093357
ABSTRACT:
An ion exchange method for the separation of hemoglobin A.sub.1 from its Schiff base precursors and from nonglycosylated hemoglobin in a sample of human blood. The known method of lysing the sample, using it to impregnate a weak cation exchange resin, eluting out the glycosylated components with a buffer solution containing from about 0.6 M to about 0.11 M alkali metal ion dissolved therein, and recovering the eluate, is modified by the inclusion of a dihydroxyboryl compound in either the hemolysate, the elution buffer, or both.
REFERENCES:
patent: 4142855 (1978-03-01), Acuff
patent: 4142856 (1978-03-01), Acuff
patent: 4142857 (1978-03-01), Acuff
patent: 4142858 (1978-03-01), Acuff
patent: 4168147 (1979-09-01), Acuff
patent: 4238196 (1980-12-01), Acuff
patent: 4243534 (1981-01-01), Bulbenko
patent: 4269605 (1981-05-01), Dean
Bunn et al., "Chromatographic Analysis of Glycosylated Hemoglobin", Advances in Hemoglobin Analysis, pp. 83-94, Alan R. Liss, Inc., NY (1981).
Bunn et al., Science, 200, pp. 21-27 (1978).
Chou et al., Clin. Chem., 24(10), pp. 1708-1710 (1978).
F. Maquart et al., Clinica Chimica Acta, 108(2), 329-332 (1980).
Goldstein et al., Diabetes, 29, pp. 623-628 (1980).
Svendsen et al., Diabetologia, 19, pp. 130-136 (1980).
Widness et al., J. Lab. Clin. Med., 95(3), pp. 386-394 (1980).
Hanamoto Mark S.
Tanaka Steve K.
Bio-Rad Laboratories, Inc.
Marantz Sidney
LandOfFree
Method for eliminating glucose dependent Schiff base effect from does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for eliminating glucose dependent Schiff base effect from, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for eliminating glucose dependent Schiff base effect from will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1275973