Combinatorial chemistry technology: method – library – apparatus – Method of screening a library – By measuring the ability to specifically bind a target...
Reexamination Certificate
2011-07-19
2011-07-19
Wessendorf, T. D. (Department: 1639)
Combinatorial chemistry technology: method, library, apparatus
Method of screening a library
By measuring the ability to specifically bind a target...
C506S007000, C506S003000, C435S004000, C435S006120, C435S007100, C536S022100, C536S023100, C536S023400
Reexamination Certificate
active
07981842
ABSTRACT:
A method is provided for identifying complexes between a transcription factor and another protein, such as another different transcription factor. The method includes the steps of isolating from a biological sample transcription factor complexes based on whether the transcription factor complexes include a particular type of transcription factor; and identifying which of the multiple different proteins are present in the isolated transcription factor complexes.
REFERENCES:
patent: 5403712 (1995-04-01), Crabtree et al.
patent: 5563036 (1996-10-01), Peterson et al.
patent: 5578444 (1996-11-01), Edwards et al.
patent: 5738990 (1998-04-01), Edwards et al.
patent: 5744131 (1998-04-01), Edwards et al.
patent: 5747253 (1998-05-01), Ecker et al.
patent: 5804374 (1998-09-01), Baltimore et al.
patent: 5849493 (1998-12-01), Montminy et al.
patent: 5859227 (1999-01-01), Giordano et al.
patent: 5861246 (1999-01-01), Weissman et al.
patent: 5908750 (1999-06-01), Reed et al.
patent: 5981188 (1999-11-01), Barbosa et al.
patent: 6040138 (2000-03-01), Lockhart et al.
patent: 6051373 (2000-04-01), Green et al.
patent: 6066452 (2000-05-01), Weissman et al.
patent: 6100032 (2000-08-01), Kern et al.
patent: 6100035 (2000-08-01), Kauffman et al.
patent: 6114503 (2000-09-01), Wei et al.
patent: 6150090 (2000-11-01), Baltimore et al.
patent: 6153383 (2000-11-01), Verdine et al.
patent: 6156502 (2000-12-01), Beattie
patent: 6156511 (2000-12-01), Schatz et al.
patent: 6171798 (2001-01-01), Levine et al.
patent: 6180763 (2001-01-01), Sherr et al.
patent: 6183956 (2001-02-01), Sivaraja et al.
patent: 6183965 (2001-02-01), Verdine et al.
patent: 6194171 (2001-02-01), Pulst et al.
patent: 6194638 (2001-02-01), Dhugga et al.
patent: 6197580 (2001-03-01), Susulic et al.
patent: 6252137 (2001-06-01), Harder et al.
patent: 6391572 (2002-05-01), Zhang et al.
patent: 6458530 (2002-10-01), Morris et al.
patent: 6537749 (2003-03-01), Kuimelis et al.
patent: 6696256 (2004-02-01), Li
patent: 6821737 (2004-11-01), Li
patent: 6924113 (2005-08-01), Li
patent: 6998240 (2006-02-01), Hoffmann et al.
patent: 2001/0053519 (2001-12-01), Fodor et al.
patent: 2002/0168640 (2002-11-01), Li et al.
patent: 2003/0148287 (2003-08-01), Li et al.
patent: 2004/0132090 (2004-07-01), Li
patent: 2004/0214166 (2004-10-01), Li
patent: 2005/0244854 (2005-11-01), Cahill et al.
patent: WO 99/10535 (1999-03-01), None
patent: WO 99/19510 (1999-04-01), None
patent: WO 00/04196 (2000-01-01), None
patent: WO 00/34435 (2000-06-01), None
patent: WO 01/16605 (2001-03-01), None
patent: WO 02/38734 (2002-05-01), None
patent: WO 02/052037 (2002-07-01), None
Pomerantz et al, Science, 267, 1995, 93-96.
Ginalski et al. Nuc. Ac. Res., 2005, 33, 1874.
Li, “Method and Kit for Isolating DNA Probes That Bind to Activated Transcription Factors”, U.S. Appl. No. 09/877,738, filed Jun. 8, 2001 (701).
Li, “Method, Array and Kit for Detecting Activated Transcription Factors by Hybridization Array”, U.S. Appl. No. 09/877,243, filed Jun. 8, 2001 (702).
Li, “Method for Identifying a Disease State Based on a Detected Mixture for Activated Transcription Factors”, U.S. Appl. No. 09/877,403, filed Jun. 8, 2001 (703).
Li, “Method for Screening for Drug Candidates for Modulating Transcription Factor Activity”, U.S. Appl. No. 09/877,705, filed Jun. 8, 2001 (704).
Thiel, Karl A., “Understanding Your Inner Transistor Radio: The Large-Scale Study of Gene Regulation”, http://www.doubletwist.com
ews/co.../article.jhtml?section=weekly01name=weekly011, May 26, 2000.
Van Brunt, Jennifer (Editor), “Systems Biology in the Post-Genomics Era”, http://www.recap.com/signal.../0A9F0F7DD2D0IBBE88256874004CI43C?, Jan. 28, 2000.
Takahashi, Nobuaki et al., “High-density cDNA filter analysis of the expression profiles of the genes preferentially expressed in human brain”,Gene, Jun. 9, 1995, vol. 164, pp. 219-227.
Zhao, Nanding et al., “High-density cDNA filter analysis: a novel approach for large-scale, quantitative analysis of gene expression”,Gene, Jan. 2, 1995, vol. 156, pp. 207-213.
Pisetsky, David S. et al., “Binding Specificity of a Monoclonal Anti-DNA Antibody”,Molecular Immunology, Sep. 16, 1981, vol. 19, No. 5, pp. 645-650.
Broude, Natalia E. et al., “Enhanced DNA sequencing by hybridization”,Proc. Natl. Acad. Sci., Apr. 1994, vol. 91, pp. 3072-3076.
Kallioniemi, Anne et al., “Comparitive Genomic Hybridization for Molecular Cytogenic Analysis of Solid Tumors”,Science, Oct. 30, 1992, vol. 258, pp. 818-821.
Velculescu, Victor E. et al., “Serial Analysis of Gene Expression”,Science, Oct. 20, 1995, vol. 270, pp. 484-487.
Nallur, G.N. et al., “Multiplex Selection Technique (MuST): An Approach to clone trascription factor binding sites”,Proc. Natl. Acad. Sci., Feb. 1996, vol. 6, No. 93, pp. 1184-1189.
Meier-Ewert, Sebastian et al., “An automated approach to generating expressed sequence catalogues”,Nature, Jan. 28, 1993, vol. 361, pp. 375-376.
Barringer, Kevin J. et al., “Blunt-end and single-strand ligations byEscherichia coliligase: influence on an in vitro amplification scheme”,Gene, Dec. 6, 1989, vol. 89, pp. 117-122.
Bussow, Konrad et al., “A method for global protein expression and antibody screening on high-density filters of an arrayed cDNA library”,Nucleic Acids Research, Sep. 10, 1998, vol. 26, No. 21, pp. 5007-5008.
Vaughan, Tristan J. et al., “Human Antibodies with Sub-nanomolar Affinities Isolated from a Large Non-immunized Phage Display Library”,Nature Biotechnology, Mar. 1996, vol. 14, pp. 309-314.
Greenberg, Michael E. et al., “Stimualtion of 3T3 cells induces transcription of the c-fos proto-oncogene”,Nature, Oct. 4, 1984, vol. 311, pp. 433-438.
Ward, E. Sally et al., “Binding activities of a repertoire of single immunoglobulin variable domains secreted fromEscherichia coli”, Nature, Oct. 12, 1989, vol. 341, pp. 544-546.
Prooijen-Knegt, A. C. Van et al., “In Situ Hybridization of DNA Sequences in Human Metaphase Chromosomes Visualized by an Indirect Fluorescent Immunocytochemical Procedure”,Experimental Cell Research, Mar. 10, 1982, vol. 141, pp. 397-407.
Coutlee, Francois et al., “Nonisotopic Detection of RNA in an Enzyme Immunoassay Using a Monoclonal Antibody against DNA-RNA Hybrids”,Analytical Biochemistry, Feb. 13, 1989, vol. 181, pp. 153-162.
Lee, Youn-Ho et al., “Reusable cDNA Libraries Coupled to Magnetic Beads”,Analytical Biochemistry, 1992, vol. 206, pp. 206-210.
Lennon, Gregory G. et al., “Hybridization analyses of arrayed cDNA libraries”,Perspectives, Oct. 1991, vol. 7, No. 10, pp. 314-317.
Boguslawski, Sophie J. et al., “Characterization of monoclonal antibody to DNA RNA and its application to immunodetection of hybrids”,Journal of Immunological Methods, Dec. 17, 1985, vol. 89, pp. 123-130.
Eberwine, James et al., “Analysis of gene expression in single live neurons”,Proc. Natl. Acad. Sci., Apr. 1992, vol. 89, pp. 3010-3014.
Guatelli, John C. et al., “Isothermal, in vitro amplification of nucleic acids by a multienzyme reaction modeled after retrovial replication”,Proc. Natl. Acad. Sci., Mar. 1990, vol. 87, pp. 1874-1878.
Marshall, Christopher J., “Tumor Suppressor Genes”,Cell, Jan. 25, 1991, vol. 64, pp. 313-326.
Wu, Dan Y. et al., “The Ligation Amplification Reaction (LAR)—Amplification of Specific DNA Sequences Using Sequential Rounds of Template-Dependent Ligation”,Genomics, Dec. 28, 1988, vol. 4, pp. 560-569.
Palazzolo, Michael J. et al., “Phage lambda cDNA cloning vectors for subtractive hybridization, fusion-protein synthesis and Cre-loxP automatic plasmid subcloning”,Gene, Oct. 5, 1989, vol. 88, pp. 25-36.
Nguyen, Catherine et al., “Differential Gene Expression in the Murine Thymus Assayed by Quantitative Hybridization of Arrayed cDNA Clones&#x
Elrod-Erickson Monicia
Panomics, Inc.
Quine Intellectual Property Law Group P.C.
Wessendorf T. D.
LandOfFree
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