Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Patent
1997-01-15
1999-10-19
Sisson, Bradley L.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
435 6, 435 914, 435 9151, 435810, C12P 1934, C12N 1564
Patent
active
059687843
ABSTRACT:
The present invention provides novel methods for identifying gene expression patterns in mRNA populations. The methods are useful for determining differential gene expression among various cells or tissues, including cells or tissues of a target organism. The invention also provides methods of determining the frequency of gene expression in mRNA populations, thus providing a method of comparing gene expression frequency among various cells or tissues. The present invention also provides methods for isolating genes corresponding to tag sequences identified according to the methods of the present invention. Furthermore, sequences that are identified according to the present invention may be used to diagnose the presence of disease.
REFERENCES:
patent: 4900811 (1990-02-01), Sutcliffe
patent: 5242798 (1993-09-01), Sutcliffe
patent: 5508169 (1996-04-01), Deugau et al.
patent: 5656425 (1997-08-01), Kraus
patent: 5700644 (1997-12-01), Gould et al.
"ZAP Express cDNA Synthesis Kit", #200403, Stratagene, 1995.
"Lambda ZAP Express"--Internet -http://biology.quensu.ca/.sup..mu. miseners/vector.sub.-- descrip.
Andersson, et al., "Simultaneous Shotgun Sequencing of Multiple cDNA Clones", DNA Sequence--The Journal of Sequencing and Mapping, 7(2):63-70.
Brenner and Livak, "DNA fingerprinting by sampled sequencing", Proc. Natl. Acad. Sci. USA, 86:8902-8906 (1989).
Cease & Cortland, "A Vector for Facile PCR Product Cloning and Modification Generating Any Desired 4-Base 5'Overhang:pRPM", BioTechniques, 14(2):250-255 (1993).
Chollet and Kawashima, "Biotin-labeled synthetic oligodeoxyribonucleotides: chemical synthesis and uses as hybridization probes", Nucleic Acids Research, 13(5):1529-1541 (1985).
Fields, et al., "How many genes in the human genome?", Nature Genetics, 7:345-346 (1994).
Ghosh and Musso, "Covalent attachment of oligonucleotides to solid supports", Nucleic Acids Research, 15(13):5353-5372 (1987).
Gubler and Hoffman, "A simple and very efficient method for generating cDNA libraries", Gene, 25:263-269 (1983).
Hasan, et al., "A novel multistep method for generating precise unidirectional deletions using BspMI, a class-IIS restriction enzyme", Gene, 50:55-62 (1986).
Ivanova, et al., "Novel Method of Comparative Gene Expression Analysis and Identification of Differentially Expressed mRNAs", Molecular Biology, 28(6):848-853 (1995).
Jones, "An Iterative and Regenerative Method for DNA Sequencing", BioTechniques, 22(5):938-946 (1997).
Kaiser and Murray, "The Use of Phage Lambda Replacement Vectors in the Construction of Representative Genomic DNA Libraries", DNA Cloning: A Practical Approach, Edited by DM Glover, 1:1-48.
Kato, K., "Description of the entire mRNA population by a 3'end cDNA fragment generated by clas IIS restriction enzymes", Nucleic Acids Research, 23(18):3685-3690 (1995).
Lee, et al., "Sequential amplification of clone DNA as tandem multimer using class-IIS restriction enzymes", Genetic Analysis: Biomolecular Engineering, 13:139-145 (1996).
Maniatis, et al., "The Isolation of Structural Genes from Libraries of Eucaryotic DNA", Cell, 15:687-701 (1978).
Mormeneo et al., "Precise nucleotide sequence modifications with bidirectionally cleaving class-IIS excision linkers", Gene, 61:21-30 (1987).
Podhajska, et al., "Conferring New Specificities on Restriction Enzymes: Cleavage at Any Predetermined Site by Combining Adapter Oligodeoxynucleotide and Class-IIS Enzyme", Methods in Enzymology, 216:303-309 (1992).
Smith, et al., "The synthesis of oligonucleotides containing an aliphatic amino group at the 5' terminus:synthesis of fluorescent DNA primers for use in DNA sequence analysis", Nucleic Acids Research, 13(7):2399-2412 (1985).
Szybalski, W., "Universal restriction endonucleases: designing novel cleavage specificities by combining adapter oligodeoxynucleotide and enzyme moieties", Gene, 40:169-173 (1985).
Szybalski, et al., "Class-IIS restriction enzymes--a review", Gene, 100:13-26 (1991).
Unrau and Deugau, Non-cloning amplification of specific DNA fragments from whole genomic DNA digests using DNA `indexers`, Gene, 145:163-169 (1994).
White, et al., "Concatemer Chain Reaction: A Taq DNA Polymerase-Mediated Mechanism for Generating Long Tandemly Repetitive DNA Sequences", Analytical Biochemistry, 199:184-190 (1991).
Adams et al., "Complementary DNA Sequencing: Expressed Sequence Tags and Human Genome Project," Science 252:1651-1656 (1991).
Adams et al., "Sequence identification of 2,375 human brain genes," Nature 355:632-634 (1992).
Aviv and Leder, "Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose," Proc. Natl. Acad. Sci. USA 69:1408-1412 (1972).
Crystal, "Transfer of Genes to Humans: Early Lessons and Obstacles to Success," Science 270:404-410 (1995).
Fleischmann et al., "Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd," Science 269:496-512 (1995).
Fraser et al., "The Minimal Gene Complement of Mycoplasma genitalium," Science 270:397-403 (1995).
Gilliand et al., "Ch. 8: Competitive PCR for Quantitation of mRNA," in PCR Protocols: A Guide to Methods and Applications, Academic Press, Inc., pp. 60-69 (1990).
Goffeau, "Life with 482 Genes," Science 270:445-446 (1995).
Hodgkin et al., "The Nematode Caenorhabditis elegans and Its Genome," Science 270:410-414 (1995).
Kahn, "From Genome to Proteins: Looking at a Cell's Proteins," Science 270:369-370 (1995).
Lee et al., "Positive Selection of Candidate Tumor-Suppressor Genes by Subtractive Hybridization," Proc. Natl. Acad. Sci. USA 88:2825-2829 (1991).
Liang and Pardee, "Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction," Science 257:967-971 (1992).
Liang et al., "Distribution and cloning of eukaryotic mRNAs by means of differential display: refinements and optimization," Nucleic Acids Research 14:3269-3275 (1993).
Nadeau et al., "Multilocus markers for mouse genome analysis: PCR amplification based on single primers of arbitrary nucelotide sequence," Mammalian Genome 3:55-64 (1992).
Nowak, "Entering the Postgenome Era," Science 270:368-369 and 371 (1995).
Olson, "A Time to Sequence," Science 270:394-396 (1995).
Sambrook et al., "Ch. 7--Extraction, Purification, and Analysis of Messenger RNA from lukaryotic Cells," in Molecular Cloning: A Laboratory Manual, 2nd edition, vol. 1, Cold Spring Harbor Laboratory Press, pp. 7.1-7.87 (1989).
Sambrook et al., in Molecular Cloning: A Laboratory Manual, 2nd edition, vol. 2, Cold Spring Harbor Laboratory Press, p. 9.51 (1989).
Sambrook et al., in Molecular Cloning: A Laboratory Manual, 2nd edition, vol. 2, Cold Spring Harbor Laboratory Press, pp. 11.46-11.47, 11.55-11.57 (1989).
Schena et al., "Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray," Science 270:467-470 (1995).
Stratagene Cloning Systems, Product Catalog, p. 312 (1993).
Velculescu et al., "Serial Analysis of Gene Expression," Science 270:484-487 (1995).
Welsh and McClelland, "Fingerprinting genomes using PCR with arbitrary primers," Nucleic Acids Research 18:7213-7218 (1990).
Welsh et al., "Arbitrarily primed PCR fingerprinting of RNA," Nucleic Acids Research 20:4965-4970 (1992).
White et al., "The polymerase chain reaction," Trends in Genetics 5(6):185-189 (1989).
Williams, "DNA polymorphisms amplified by arbitrary primers are useful as genetic markers," Nucleic Acids Research 18:6531-6535 (1990).
Woodward et al., "Random sequence oligonucleotide primers detect polymorphic DNA products which segregate in inbred strains of mice," Mammalian Genome 3:73-78 (1992).
Research Genetics (advertisement), Nucleic Acids Research, vol. 22, No. 15, Aug. 11, 1994.
Sigma Molecular Biology (catalog), pp. 42, 43, and 108, 1989.
Sajjadi Fereydoun G.
Spinella Dominic G.
Cappellari Charles
Chugai Pharmaceutical Co., Ltd.
Gritzmacher Christine
Hake Richard A.
Sisson Bradley L.
LandOfFree
Method for analyzing quantitative expression of genes does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for analyzing quantitative expression of genes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for analyzing quantitative expression of genes will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2054703