Method and system for particle data processing

Details Method and system for particle data processing Method and system for particle data processing

2008-02-22

2009-11-03

Bui, Bryan (Department: 2863)

Data processing: measuring, calibrating, or testing

Calibration or correction system

Sensor or transducer

Reexamination Certificate

active

07613583

ABSTRACT:
In an embodiment, a computer-implemented method is provided for processing digital data from a particle analyzer. The method includes receiving digital particle data, transforming the received data to correct for noise, applying linear compensation for dye spectral overlap, and re-establishing the original dimensions of the data. Processed particle data may be used for display, analysis or storage. In another embodiment, a system comprises at least one particle analyzer coupled to a particle data corrector. The particle data corrector includes a transformer, a compensator, and a converter.

REFERENCES:
patent: 6897954 (2005-05-01), Bishop et al.
patent: 6954722 (2005-10-01), Parks et al.
patent: 2006/0259253 (2006-11-01), Ellison et al.
Howard M. Shapiro, “Practical Flow Cytometry” 3rdEdition, 1995, pp. vii-xxii, 17-19, 163-166 and 214-215, (Wiley-Liss, NY).
Mario Roederer, “Spectral Compensation for Flow Cytometry: Visualization Artifacts, Limitations, and Caveats”, Cytometry , 2001, 45: 194-205.
C. Bruce Bagwell, et al., “Fluorescence Spectral Overlap Compensation for any Numbers of Flow Cytometry Parameters”, Annals New York Academy of Sciences, 1993, 677: 167-184.
Mario Roederer, “Compensation is not Dependent on Signal Intensity or on Number of Parameters”, Cytometry (Communications in Clinical Cytometry), 2001, 46:357, Wiley-Liss.

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